How the Brain Adapts to Antidepressants: Receptors, Circuits, and Neuroplasticity

Understanding the Brain · Oct 12, 2026 · 3m · transcript

Antidepressants influence neurotransmission relatively quickly, yet meaningful clinical improvement often takes longer. This episode explores receptor signaling, neural adaptation, stress circuitry, and neuroplasticity in depression treatment. Discover why changes in brain function are more complicated than the familiar chemical-imbalance explanation.