Latest / The You Project / #2221 Peptides: Bullsh*t or Medicine? - Dr. Jeff Gross

Transcript

#2221 Peptides: Bullsh*t or Medicine? - Dr. Jeff Gross · The You Project

• 0:00
  Speaker 1: Oh, g'day, team. It's Harps and Tiff and Dr. Jeff.
• 0:03
  Speaker 2: It's the Bloody You Project. It's a beautiful day in
• 0:06
  Speaker 2: the thriving metropolis of Melbourne. And, yes, I'm going to
• 0:09
  Speaker 2: give you an unneeded, unnecessary update.
• 0:13
  Speaker 1: It's sunny. It's cold. What's the temp going to be today, Tiff?
• 0:17
  Speaker 1: Is it like 20 or something?
• 0:19
  Speaker 3: I think that all week it was around the 20s. Well,
• 0:21
  Speaker 3: spring is here, which– What do.
• 0:29
  Speaker 2: You call spring over there? You call it spring, don't you?
• 0:31
  Speaker 2: And you call autumn, you call it fall, right?
• 0:35
  Speaker 4: Yeah, or autumn, either one.
• 0:38
  Speaker 1: Autumn. Well, have you got a temp for me or no?
• 0:42
  Speaker 1: What are you doing?
• 0:46
  Speaker 3: I've just knocked everything over on my desk. There's coffee everywhere.
• 0:51
  Speaker 1: Is there really?
• 0:52
  Speaker 3: Yeah.
• 0:52
  Speaker 4: I've spilled my coffee. All right.
• 0:55
  Speaker 2: Why don't you attend to that and clean up your
• 0:58
  Speaker 2: desk that looks like a fucking 12-year-old boy's room and
• 1:05
  Speaker 2: the grown-up and I will start a conversation and you
• 1:10
  Speaker 2: just maybe mute your mic so we don't have to
• 1:13
  Speaker 2: hear you saying those rude words and all the clunking
• 1:18
  Speaker 2: and shit that you're doing. And by the way, what
• 1:21
  Speaker 2: a great contributor you are to the project. Where would
• 1:25
  Speaker 2: we be without you? Some people think further advanced. I disagree. Yeah,
• 1:31
  Speaker 2: we could be intergalactic without you, but now we're just global.
• 1:37
  Speaker 2: All right, Doc, how are you? How is life? Sorry
• 1:40
  Speaker 2: you had to put up with that.
• 1:42
  Speaker 4: Not at all.
• 1:43
  Speaker 5: It's great to be back on the You Project. Everything
• 1:47
  Speaker 5: is good here. I hope the same for all of you.
• 1:51
  Speaker 1: Yeah, thanks, man. Thank you. Have you been busy? Are
• 1:56
  Speaker 1: you as busy as ever? More busy, less busy, people
• 1:59
  Speaker 1: streaming through the door?
• 2:01
  Speaker 5: It's busier between patients and the type of activities we're
• 2:08
  Speaker 5: into and expanding and the projects particularly centered around.
• 2:14
  Speaker 4: A lot of peptide education.
• 2:16
  Speaker 3: Yeah.
• 2:17
  Speaker 2: Well, that's where we're going today. I just thought as
• 2:21
  Speaker 2: you were speaking, which is, it's a rare thing for me,
• 2:23
  Speaker 2: but I had a thought, so I'm.
• 2:24
  Speaker 1: Going to wheel it out.
• 2:25
  Speaker 2: That is, there would be people listening today for the
• 2:29
  Speaker 2: first time to you, so they know who you are
• 2:31
  Speaker 2: or what you do. Just for those newbies, what is
• 2:37
  Speaker 2: your job? What do you do? Just give the kind
• 2:41
  Speaker 2: of whatever, one minute overview of you so people know
• 2:44
  Speaker 2: who they're listening to.
• 2:47
  Speaker 4: Thank you.
• 2:48
  Speaker 5: I am a recovering neurological spine surgeon and a practice
• 2:54
  Speaker 5: in the field of cutting edge regenerative medicine using stem cells, exosomes,
• 3:00
  Speaker 5: other biologics, peptides that falls over into musculoskeletal structures, joints
• 3:08
  Speaker 5: and spine. It falls into inflammatory issues and longevity, anti-aging
• 3:14
  Speaker 5: and so much more.
• 3:16
  Speaker 1: You do indeed.
• 3:17
  Speaker 2: And it seems to be, from the outside looking in,
• 3:23
  Speaker 2: a kind of somewhat, or it can be a somewhat murky, confusing,
• 3:30
  Speaker 2: kind of conflicting, emotion-provoking area, which is why.
• 3:40
  Speaker 1: Today's chat has come about.
• 3:42
  Speaker 2: So what we're doing, everybody, is we're going to talk
• 3:44
  Speaker 2: about peptides for better or worse at the moment are, I,
• 3:51
  Speaker 2: and this is not because Dr. Jeff's here, I think
• 3:53
  Speaker 2: there's a lot of value or there can be a
• 3:55
  Speaker 2: lot of value in them. I think there's a lot
• 3:57
  Speaker 2: of hyperbole around a lot of stuff that's going on
• 4:00
  Speaker 2: at the moment, some of which is bullshit, some of
• 4:04
  Speaker 2: which is not, and I'm not.
• 4:05
  Speaker 1: Talking about peptides.
• 4:06
  Speaker 2: I'm talking more broadly about all of the things that
• 4:09
  Speaker 2: people are spruiking and endorsing and talking about in the longevity, wellness,
• 4:15
  Speaker 2: high performance space. So I want to cut out the
• 4:18
  Speaker 2: fluff today and go through some peptides that are quite popular,
• 4:23
  Speaker 2: often spoken about, what they're called, what they're meant to do,
• 4:27
  Speaker 2: and what the evidence might suggest they actually do. So
• 4:32
  Speaker 2: we're going to give everything a five out of five
• 4:34
  Speaker 2: rating or a one to five rating, I should say.
• 4:40
  Speaker 2: So let's start with something which has kind of moved.
• 4:47
  Speaker 1: Out of the niche.
• 4:48
  Speaker 2: I don't know if this is out of the niche
• 4:51
  Speaker 2: and into more mainstream thinking and culture, which is semaglutide.
• 4:56
  Speaker 2: So here's what it's meant to do. Appetite suppression, weight loss,
• 5:01
  Speaker 2: glucose control, cardiometabolic benefits. And AI has given it a
• 5:08
  Speaker 2: five out of five rating for what it's meant to do.
• 5:12
  Speaker 1: And Dr. Jeff, discuss.
• 5:16
  Speaker 5: Semi-glutide has been a game changer and opens the door
• 5:20
  Speaker 5: for many other peptides I'm sure we'll talk about. We're
• 5:24
  Speaker 5: cutting into obesity, which is the driver of all kinds
• 5:29
  Speaker 5: of other diseases based upon that poorly regulated metabolism.
• 5:35
  Speaker 4: Is key.
• 5:36
  Speaker 5: So semi-glutide does move the needle significantly. And it is,
• 5:42
  Speaker 5: we'll call it sort of an early tool in the
• 5:44
  Speaker 5: GLP-1 group. And although it does meet the metrics of
• 5:52
  Speaker 5: what it sets out to do, I wouldn't give it
• 5:54
  Speaker 5: a five out of the five like the internet does.
• 5:57
  Speaker 5: I would give it a four out of five because
• 5:59
  Speaker 5: we have better ones now. And I have to leave
• 6:02
  Speaker 5: room to score those better above blue tide.
• 6:08
  Speaker 1: What are the potential downsides?
• 6:11
  Speaker 2: Like what are the, maybe some of the negative symptoms
• 6:14
  Speaker 2: that can not necessarily do, but can arise?
• 6:18
  Speaker 4: Well, at first you got to inject yourself. So you
• 6:20
  Speaker 4: have to be open to that.
• 6:22
  Speaker 5: Second, and although that's fairly straightforward because diabetics taking insulin
• 6:27
  Speaker 5: have done that for decades, it can cause a little
• 6:32
  Speaker 5: bit of, you know, sight irritation and things like that. Second,
• 6:37
  Speaker 5: you can have constipation. It slows the GI tract significantly.
• 6:41
  Speaker 5: That's probably the number one issue. You can have nausea,
• 6:45
  Speaker 5: particularly at the beginning or at a change of dose
• 6:49
  Speaker 5: and vomiting even. You can have, there's a very rare
• 6:55
  Speaker 5: incidence of single eye sudden blindness.
• 6:59
  Speaker 4: Wow. Which is not insignificant.
• 7:02
  Speaker 5: And then there are some reported cases of pancreatitis.
• 7:08
  Speaker 2: Yeah.
• 7:09
  Speaker 4: Wow.
• 7:10
  Speaker 1: So what's that like inflammation of the pancreas?
• 7:13
  Speaker 5: Yeah, but that can really mess you up and cause,
• 7:16
  Speaker 5: itself cause diabetes because then you can't make your own instance.
• 7:19
  Speaker 1: Yeah, exactly.
• 7:20
  Speaker 2: Your pancreas produces insulin. Yeah, the whole slowing of gastric emptying,
• 7:28
  Speaker 2: meaning we've literally got shit in our body for longer,
• 7:32
  Speaker 2: that worries me. I don't like the idea of that
• 7:36
  Speaker 2: just being in my body for five days when it
• 7:38
  Speaker 2: could be in for one or two. I'm not sure
• 7:41
  Speaker 2: about that one. That's a bit of a deterrent. You
• 7:44
  Speaker 2: don't need to, Tiff, but if you needed to or
• 7:47
  Speaker 2: you're in a body where this might be a considered treatment,
• 7:54
  Speaker 2: would you use something like semaglutide or a GLP-1?
• 8:00
  Speaker 3: I think that's a really hard question to answer when
• 8:02
  Speaker 3: you're not in the situation.
• 8:05
  Speaker 2: That is a good answer without giving an answer.
• 8:09
  Speaker 1: Well done. I think you should go into politics.
• 8:12
  Speaker 3: Well, here's my reasoning. A few years ago, anti-ADHD medication,
• 8:18
  Speaker 3: completely anti it, then opened to trying it on as needed,
• 8:21
  Speaker 3: and now I'm currently using it. And so far, it's
• 8:25
  Speaker 3: been brilliant.
• 8:27
  Speaker 1: Good answer. I like it.
• 8:29
  Speaker 5: All right.
• 8:31
  Speaker 2: Next peptide on the list is Terzepatide.
• 8:35
  Speaker 1: Did I say that correct, Doc?
• 8:37
  Speaker 4: You did.
• 8:37
  Speaker 1: Okay.
• 8:39
  Speaker 2: Oh, supposedly weight loss, appetite regulation, improved glucose. It kind
• 8:45
  Speaker 2: of sounds a bit like the first one, insulin sensitivity.
• 8:49
  Speaker 2: One of the strongest, this is chatters, strongest examples of
• 8:52
  Speaker 2: a peptide producing substantial reproducible changes in human body composition
• 8:58
  Speaker 2: also gets a five out of five on the interwebs,
• 9:01
  Speaker 2: which of course is not Dr.
• 9:04
  Speaker 1: Jeff. What are your thoughts on this one?
• 9:07
  Speaker 4: Yeah, I give this one a four and a half
• 9:09
  Speaker 4: out of five.
• 9:10
  Speaker 5: It is in the same GLP-1 family, does all the
• 9:14
  Speaker 5: same things that semaglutide does that we just discussed, but better.
• 9:18
  Speaker 5: They're head-to-head competitions. They're now showing with both of these
• 9:25
  Speaker 5: that terzepatide, you can lose more weight and lose.
• 9:27
  Speaker 4: It faster if it's just about that.
• 9:30
  Speaker 5: And of course, when we say weight, there's a more
• 9:34
  Speaker 5: granular discussion we'll get into when we talk about some
• 9:36
  Speaker 5: other peptides about body composition, not just weight, but the, um,
• 9:41
  Speaker 5: terzepatide is, uh, less associated with those nasty side.
• 9:46
  Speaker 4: Effects that are rare.
• 9:48
  Speaker 5: Uh, but it hasn't been around as long, so maybe
• 9:52
  Speaker 5: we'll just keep watching it, but it's moving up the
• 9:56
  Speaker 5: efficacy chain in the GLP-1 family.
• 10:01
  Speaker 2: So with this and semaglutide and other GLP-1s, these are
• 10:07
  Speaker 2: daily injections?
• 10:09
  Speaker 4: No. These two are weekly.
• 10:14
  Speaker 5: They are one of the few– This group is one
• 10:17
  Speaker 5: of the few in the peptide family that are not
• 10:20
  Speaker 5: specifically made by the body in that form. We do
• 10:24
  Speaker 5: make GLP-1 in our body, but it doesn't last very long.
• 10:28
  Speaker 5: So these semaglutide, trisepatide, retatrutide, they have been modified very
• 10:35
  Speaker 5: slightly to last longer. They last five to seven days,
• 10:39
  Speaker 5: depending on which one in the body. And that's why
• 10:41
  Speaker 5: it's a weekly injection.
• 10:43
  Speaker 1: And I guess that's subcutaneous, not IM.
• 10:47
  Speaker 4: Correct.
• 10:47
  Speaker 5: It's just a little Botox needle goes in five sixteenths
• 10:52
  Speaker 5: of an inch.
• 10:54
  Speaker 4: Yeah. Yeah. Perfect.
• 10:56
  Speaker 2: Well, speaking of Reddit True Tide, this is the one that,
• 11:02
  Speaker 2: you know, on my feeds anyway, gets lots of attention
• 11:06
  Speaker 2: and talk and endorsement from all the Buffheads and the Meatheads.
• 11:10
  Speaker 1: God bless them. We love our Buffhead community.
• 11:14
  Speaker 2: And there's a couple of high profile, bodybuilders is one
• 11:19
  Speaker 2: particular whose name escapes me. It'll come to me, but
• 11:21
  Speaker 2: he's he's got a Ph.D. and he's a bodybuilder and
• 11:24
  Speaker 2: he's all over this.
• 11:26
  Speaker 1: He's like, this is this is the shit.
• 11:30
  Speaker 2: So read a true tied weight loss, metabolic improvements, targets
• 11:34
  Speaker 2: GLP one plus G.
• 11:37
  Speaker 1: G IP plus glucagon. It gets a four.
• 11:42
  Speaker 2: And the commentary is the next generation obesity peptide.
• 11:45
  Speaker 1: Everyone is watching.
• 11:47
  Speaker 2: Phase three data has shown very large weight reductions, but
• 11:51
  Speaker 2: it remains investigational. My kind of take on this, according
• 11:57
  Speaker 2: to the genii on Instagram, which of course is the
• 12:00
  Speaker 2: world's best resource for everything, is that it helps you
• 12:03
  Speaker 2: maintain muscle mass unlike some of the others.
• 12:08
  Speaker 5: Yeah, let's dig in here. This one gets a five
• 12:10
  Speaker 5: out of five. And the only reason it got a
• 12:12
  Speaker 5: four out of five is because all the AIs are
• 12:15
  Speaker 5: biased and And use sort of government and regulatory websites
• 12:20
  Speaker 5: to say that's investigational. It's non-investigational. Retitutide has three mechanisms,
• 12:27
  Speaker 5: as you listed. Terzepatide has two. Semiglutide has one. So
• 12:31
  Speaker 5: you don't need as much GLP-1 in the retitutide system.
• 12:36
  Speaker 5: And therefore, you have a less gastrointestinal slowness. There's some,
• 12:41
  Speaker 5: but you lose the weight faster with fewer side effects.
• 12:44
  Speaker 5: More maintenance of muscle comes out of that. And we're
• 12:48
  Speaker 5: now showing it reversing fatty liver in some people. So
• 12:52
  Speaker 5: Reddit True Tide is a game changer. It's well-studied, well-published.
• 12:57
  Speaker 5: It's not investigational. The only reason it's not yet out
• 13:01
  Speaker 5: on the market is the owner of all three of
• 13:03
  Speaker 5: these is one company. And that one company is going
• 13:06
  Speaker 5: to wait until they eke every dollar out of the truzepatide,
• 13:10
  Speaker 5: which is the favorite child. And then as that patent
• 13:16
  Speaker 5: wears off, they will then all of a sudden release
• 13:20
  Speaker 5: the retatrutide.
• 13:22
  Speaker 4: So now you can get retatrutide. compounded.
• 13:26
  Speaker 5: And I will say this, because this is a show
• 13:28
  Speaker 5: where I can share this. I've heard twice in the
• 13:31
  Speaker 5: last 72 hours that the Eli Lilly branded Reddit true
• 13:35
  Speaker 5: tie may have an issue. And that issue might be
• 13:41
  Speaker 5: borderline conspiracy theory. But since the puppet masters that created
• 13:46
  Speaker 5: COVID didn't kill off as many people as they wanted to,
• 13:50
  Speaker 5: They are doing something with the retatrutide from the brand.
• 13:54
  Speaker 5: So people are suggesting that the non-Eli Lilly brand, meaning
• 13:59
  Speaker 5: the compounded branded, where you can get it direct from
• 14:05
  Speaker 5: someone who can make peptides, as long as it's third-party tested,
• 14:08
  Speaker 5: and this goes for all peptides, third-party tested, no impurities,
• 14:12
  Speaker 5: no toxins, all the cleansing agents are removed, and it
• 14:15
  Speaker 5: is exactly what it says it is.
• 14:17
  Speaker 4: Because if you get them on Tmoo, it's not.
• 14:20
  Speaker 1: Always.
• 14:21
  Speaker 4: So that that may be a safer way to go.
• 14:24
  Speaker 5: Now, I haven't confirmed that, but I've heard it twice
• 14:27
  Speaker 5: from reputable sources in the last 72 hours.
• 14:29
  Speaker 4: So I'm a little concerned.
• 14:33
  Speaker 1: Is this something that your patients use?
• 14:38
  Speaker 5: Yes, we have quite a few that are benefiting and
• 14:41
  Speaker 5: have benefited from it. I personally use it not for
• 14:46
  Speaker 5: fat loss anymore, but for body composition, maintenance, control of hunger,
• 14:53
  Speaker 5: metabolic functioning. My HbA1c is 5.0 and I would like to.
• 15:00
  Speaker 4: Continue to drive it down. It's a longevity marker to
• 15:03
  Speaker 4: drive it down. Yeah, yeah.
• 15:05
  Speaker 1: Awesome. And again, once a week, Sub-Q injection? Yep, exactly.
• 15:11
  Speaker 4: Just a low enough dose. We call that microdosing, but
• 15:14
  Speaker 4: it's just a lower dose.
• 15:16
  Speaker 1: Yeah.
• 15:17
  Speaker 2: And so when that kind of gets wheeled out from
• 15:20
  Speaker 2: behind the pharmaceutical curtain, will that make tazepatide and semaglutide
• 15:27
  Speaker 2: somewhat redundant.
• 15:30
  Speaker 1: When it gets wheeled out officially?
• 15:33
  Speaker 5: It'll make it open to generic brands and less expensive.
• 15:37
  Speaker 5: So the semi-glutide and terzapatide still work. They'll, they'll be
• 15:41
  Speaker 5: reasonably desirable still in the marketplace. Uh, the ritatrutide will
• 15:47
  Speaker 5: be the, you know, the, the one that people reach for,
• 15:51
  Speaker 5: particularly if their insurance pays for it or if they,
• 15:55
  Speaker 5: they want to pay for it themselves.
• 15:57
  Speaker 2: Yeah.
• 15:57
  Speaker 4: Right.
• 15:59
  Speaker 2: Um, So last one kind of in this space is tessamorelin.
• 16:05
  Speaker 2: Am I pronouncing that correctly?
• 16:08
  Speaker 5: You are, but I wouldn't put it in this space
• 16:10
  Speaker 5: except that it's in a group of peptides that stimulate
• 16:18
  Speaker 5: a little extra release of growth hormone from your pituitary
• 16:22
  Speaker 5: gland at night. That's when we release it. Because even
• 16:26
  Speaker 5: though you stop growing tall... you still want your tissues
• 16:31
  Speaker 5: to develop and grow internally, muscles, bone.
• 16:34
  Speaker 4: Density, things like that.
• 16:35
  Speaker 5: So tesamorelin can increase that growth hormone pulse at night,
• 16:42
  Speaker 5: and it helps maintain and gain muscle. Tesamorelin specifically reduces
• 16:48
  Speaker 5: visceral fat also. So it's a metabolic switch. So that
• 16:53
  Speaker 5: is something we pair often. or something in that family,
• 16:56
  Speaker 5: we pair often with a GLP because as you're losing weight,
• 17:00
  Speaker 5: you do lose some muscle mass. And to preserve that
• 17:04
  Speaker 5: along that journey or early or late on that journey,
• 17:07
  Speaker 5: you should, you know, besides doing all the right work,
• 17:10
  Speaker 5: the exercises, the heavy lifting, the weight bearing, the protein intake,
• 17:17
  Speaker 5: this is a little tweak that can help and we
• 17:20
  Speaker 5: use it often.
• 17:21
  Speaker 2: Right. So their commentary, reduction of visceral abdominal fat, which
• 17:28
  Speaker 2: you said they've given it a four out of five.
• 17:31
  Speaker 2: And the commentary is important because this isn't purely a
• 17:35
  Speaker 2: biohacking compound, has an established therapeutic use.
• 17:40
  Speaker 4: Does that sound about right to you? Yeah, so here's
• 17:42
  Speaker 4: why AI is biased.
• 17:44
  Speaker 5: This one is actually approved in the US for certain ailments.
• 17:49
  Speaker 5: So by approved, again, approved means marketing, approve a marketing claim,
• 17:53
  Speaker 5: but the only thing our FDA approves is marketing. So
• 17:58
  Speaker 5: it's out there for that reason. And the AI says
• 18:02
  Speaker 5: it's not investigational. It's no different in my mind from
• 18:05
  Speaker 5: any of the other in its family. They haven't studied
• 18:08
  Speaker 5: and tested just because a government committee latched onto one
• 18:13
  Speaker 5: and disregarded the others doesn't mean that the others are
• 18:16
  Speaker 5: necessarily worse.
• 18:19
  Speaker 1: Right, now I'm going to switch it up.
• 18:21
  Speaker 2: I'm going to tell you about this peptide, but I'm
• 18:24
  Speaker 2: not going to tell you the name, and then you're
• 18:26
  Speaker 2: going to guess the peptide.
• 18:28
  Speaker 5: All right.
• 18:29
  Speaker 1: I think you'll get it.
• 18:31
  Speaker 2: Okay, so allegedly, no early guessing, allegedly tissue repair, tendon
• 18:38
  Speaker 2: ligament recovery, wound healing, gut health, probably the most famous
• 18:44
  Speaker 2: healing peptide, enormous interest, but human evidence remains limited. The
• 18:49
  Speaker 2: interwebs has given it a one out of five, which
• 18:55
  Speaker 2: my training partner uses this and swears by it and
• 19:00
  Speaker 2: loves it and has seen, you know, all anecdotal, everyone.
• 19:04
  Speaker 1: We get it, but he swears by this. What's your guess?
• 19:08
  Speaker 4: Well, this is, this is an easy one. It's probably
• 19:11
  Speaker 4: the most popular one.
• 19:12
  Speaker 5: non-GLP peptide out there it's BPC 157 it's body protection
• 19:17
  Speaker 5: compound it is naturally occurring in your body it is
• 19:21
  Speaker 5: well studied for a long time there are even dose
• 19:26
  Speaker 5: escalation studies and giving this to people IV.
• 19:31
  Speaker 4: The interwebs give it a 1 out of 5 I'd
• 19:34
  Speaker 4: give it a 5 out of 5.
• 19:35
  Speaker 5: It's an essential healing and recovery an anti-inflammatory peptide.
• 19:41
  Speaker 1: Yeah That's so funny, isn't it?
• 19:43
  Speaker 2: When I was reading that and I went, oh yeah,
• 19:45
  Speaker 2: and then I got to the rating and I'm like,
• 19:47
  Speaker 2: how is it getting a one? Again, I'm not, I'm
• 19:51
  Speaker 2: not recommending this anyone, but I'm just talking about my
• 19:55
  Speaker 2: interaction with it, with people that I know. And the
• 20:00
  Speaker 2: crab is one of many. If I reckon you and
• 20:03
  Speaker 2: I should give that a bit of a go post-training,
• 20:06
  Speaker 2: Years ago.
• 20:07
  Speaker 3: And I'm not sure if taking it orally is as good,
• 20:11
  Speaker 3: maybe Dr. Jeff can tell us, but I was taking
• 20:13
  Speaker 3: it when I was sparring and because I'd had a
• 20:16
  Speaker 3: conversation around the potential protective mechanisms for your brain. And
• 20:21
  Speaker 3: then I couldn't get it anymore.
• 20:24
  Speaker 1: And what did you notice though when you took it?
• 20:26
  Speaker 3: Look, I didn't feel that I had a lot of
• 20:30
  Speaker 3: niggles with training and a lot of, you know, those
• 20:33
  Speaker 3: types of things. So I'm not sure. I'm not sure.
• 20:37
  Speaker 4: Yeah.
• 20:38
  Speaker 3: Yeah.
• 20:38
  Speaker 1: Yeah.
• 20:39
  Speaker 2: Yeah.
• 20:40
  Speaker 1: Go doc.
• 20:41
  Speaker 5: I take plenty of it. It's so it's, it's part
• 20:44
  Speaker 5: of a stack. I take, we'll get into the maybe
• 20:45
  Speaker 5: stacks at the end, but the, um, BPC one five
• 20:49
  Speaker 5: seven is one of the few peptides you can take
• 20:51
  Speaker 5: orally for the GI tract. It's made by the GI
• 20:55
  Speaker 5: tract and supports the GI tract separate from its musculoskeletal
• 21:00
  Speaker 5: and other anti-inflammatory and healing properties. Um, The bioavailability, meaning
• 21:04
  Speaker 5: how much is getting into your body from a subcutaneous injection,
• 21:07
  Speaker 5: is probably around 90%. From an oral, you're looking at 5%
• 21:11
  Speaker 5: to 10%. So you have to up-dose the oral to
• 21:14
  Speaker 5: get anywhere close to an injection which is superior for delivery.
• 21:21
  Speaker 1: Yeah, yeah.
• 21:23
  Speaker 2: One of my friends who takes nothing, he's an ex-AFL player,
• 21:27
  Speaker 2: the equivalent in the States being an NFL player, and he....
• 21:34
  Speaker 1: How do I not throw him under the bus?
• 21:36
  Speaker 2: So he just played a– he's only 40, so he's
• 21:40
  Speaker 2: not 63, or he might be 39.
• 21:43
  Speaker 1: He just played a kind of a– what was it?
• 21:48
  Speaker 2: It's kind of a local football game for like recently,
• 21:54
  Speaker 2: and he hasn't played for a few years, but he's
• 21:56
  Speaker 2: still in good shape. But he was super sore. for
• 21:59
  Speaker 2: like two days, real sore. And then one of his
• 22:02
  Speaker 2: mates gave him some BPC-157. And he said he woke
• 22:08
  Speaker 2: up the next day with zero soreness.
• 22:11
  Speaker 1: And he's like, like zero. And he said, mate, I
• 22:16
  Speaker 1: could hardly move.
• 22:17
  Speaker 2: And I said, well, that's either really effective or the
• 22:20
  Speaker 2: best placebo on the planet. Or, you know, I think
• 22:24
  Speaker 2: there's probably some. And again, this is not an endorsement.
• 22:27
  Speaker 2: I haven't used it, but I know a few people
• 22:29
  Speaker 2: who do. That's not legal in Australia, is it, Tiff?
• 22:32
  Speaker 2: Like none of these are.
• 22:33
  Speaker 4: Really, are they?
• 22:35
  Speaker 3: It wasn't back when I was looking at it. I'm
• 22:36
  Speaker 3: not sure if that's changed, but I don't think so.
• 22:39
  Speaker 1: Yeah, yeah. It's so weird. All right, next one. TB500.
• 22:48
  Speaker 2: What it does, tissue repair, wound healing, recovery and mobility.
• 22:52
  Speaker 2: The story is it's often paired conceptually with BPC-157 as
• 22:57
  Speaker 2: the recovery stack. And not surprisingly, the rating is one
• 23:03
  Speaker 2: out of five.
• 23:04
  Speaker 1: Doc?
• 23:07
  Speaker 3: Yes.
• 23:07
  Speaker 5: So again, this is highly studied dose escalation. It's well published.
• 23:13
  Speaker 5: It's a five out of five. It's often paired with
• 23:15
  Speaker 5: BPC-157 because the two have synergy. both in recovery, regeneration,
• 23:22
  Speaker 5: suppression of inflammation. The two together are the base of
• 23:26
  Speaker 5: what we often call the Wolverine protocol, you may have heard,
• 23:30
  Speaker 5: which is recovery protocol, because the Wolverine can heal himself
• 23:35
  Speaker 5: like your colleague in the AFL.
• 23:38
  Speaker 4: So this is very common. We use it. It's from
• 23:41
  Speaker 4: the thymus gland.
• 23:43
  Speaker 5: TB500 is a synthetic version of It's called thymusin beta-4.
• 23:50
  Speaker 4: It's a fragment of a thymus protein.
• 23:54
  Speaker 5: Now, you don't hear much about the thymus gland. When
• 23:57
  Speaker 5: you're an infant, it has a lot of activity. It's
• 24:01
  Speaker 5: kind of giving the immune system going. And there's another
• 24:06
  Speaker 5: thymus peptide maybe we'll talk about later that's good for
• 24:08
  Speaker 5: the immune system too.
• 24:10
  Speaker 4: But these are incredibly powerful peptides.
• 24:14
  Speaker 3: Yeah.
• 24:15
  Speaker 1: The next one is used.
• 24:18
  Speaker 2: Quite a bit in Australia. I know quite a few
• 24:20
  Speaker 2: people who use it. It's CJC 1295.
• 24:23
  Speaker 1: Yep.
• 24:27
  Speaker 2: What it's meant to do, increase growth, hormone signaling, promoted
• 24:31
  Speaker 2: for muscle, fat loss, sleep, and recovery. The story is
• 24:37
  Speaker 2: a classic longevity clinic, peptide, fascinating GH biology, but don't
• 24:42
  Speaker 2: confuse the increased GH with proven anti-aging.
• 24:46
  Speaker 1: The score is a two.
• 24:49
  Speaker 4: Yeah, I'd give it a four out of five.
• 24:51
  Speaker 5: And I don't give it a five because we combine
• 24:56
  Speaker 5: it with some others for optimization. So it is in
• 24:59
  Speaker 5: that growth hormone secreting family like tesamorelin, ipamorelin, hexamorelin.
• 25:07
  Speaker 4: Samorelin or samorelin.
• 25:09
  Speaker 5: So they all have different approaches and you have to
• 25:14
  Speaker 5: be cautious. For example, tesamorelin can throw off your insulin sensitivity.
• 25:19
  Speaker 5: ipamorelin is less likely to so what you see out
• 25:22
  Speaker 5: there sometimes are tesamorelin ipamorelin blends tesamorelin to help get
• 25:27
  Speaker 5: that visceral fat ipamorelin to so you don't have to
• 25:30
  Speaker 5: take as much tesamorelin and still get that growth hormone
• 25:33
  Speaker 5: pulse cjc is often paired with ipamorelin and they have
• 25:38
  Speaker 5: synergy so you don't need as much so there are
• 25:42
  Speaker 5: you know we're learning more about them so i'd give
• 25:44
  Speaker 5: them a four out of five learning meaning what's the
• 25:46
  Speaker 5: best way to use them but they work.
• 25:50
  Speaker 2: Tiff, I've got a little bit of research for you
• 25:52
  Speaker 2: to do while the doc and I unpack the next one.
• 25:55
  Speaker 2: I want you to find out when the Essendon Footy
• 25:57
  Speaker 2: Club doping scandal was. I use that word doping scandal
• 26:03
  Speaker 2: in italics because it's silly. But anyway, that's what it was.
• 26:09
  Speaker 2: And what were they apparently using? I'll get back to
• 26:13
  Speaker 2: you in two minutes. All right, next one, doc. As
• 26:16
  Speaker 2: you just mentioned, Ipa Morellon. Growth hormone release, promoted for recovery,
• 26:22
  Speaker 2: sleep and body composition, often combined with CJC 1295 to
• 26:28
  Speaker 2: stimulate the GH axis.
• 26:30
  Speaker 1: The score they give it is a two.
• 26:34
  Speaker 5: Yeah, CJC and nipamirelin together are five, especially if you're
• 26:38
  Speaker 5: on a GLP, losing weight and worried or actually losing muscle.
• 26:44
  Speaker 5: And this is where body composition testing works.
• 26:47
  Speaker 4: Is so important. And we've talked about this before.
• 26:49
  Speaker 5: On the you project, but you know, just measuring your
• 26:53
  Speaker 5: weight isn't enough when you really want to make body
• 26:56
  Speaker 5: compositional changes.
• 26:58
  Speaker 1: Yes.
• 26:58
  Speaker 5: Fat will be the main thing you lose, but it's
• 27:00
  Speaker 5: not the only thing. And if you want to maintain
• 27:03
  Speaker 5: that muscle or gain muscle while you're losing fat, then
• 27:07
  Speaker 5: you need a fat, the, the body, the entire weight
• 27:11
  Speaker 5: loss medicine is, plus the muscle maintenance and gain peptide
• 27:16
  Speaker 5: at the same time.
• 27:18
  Speaker 2: Yeah.
• 27:18
  Speaker 1: Yeah. Perfect. I have not heard of this one.
• 27:25
  Speaker 2: Sermorelin, S-E-R-M-O-R-E-L-I-N, stimulates endogenous GH release. It's an older secretagogue
• 27:38
  Speaker 2: concept that's resurfaced in longevity medicine.
• 27:42
  Speaker 1: It gets a three.
• 27:45
  Speaker 5: So this is a little bit older in the family
• 27:48
  Speaker 5: of growth hormone releasers. And the word, this is your
• 27:51
  Speaker 5: Scrabble word, you just said it, secretagogue. It's a medicine
• 27:56
  Speaker 5: or a peptide that stimulates the secretion thereof. So we're
• 28:02
  Speaker 5: stimulating the secretion of growth hormone. And naturally, our body
• 28:07
  Speaker 5: does that. We make up a hormone that stimulates the
• 28:11
  Speaker 5: growth hormone release.
• 28:11
  Speaker 4: Why?
• 28:12
  Speaker 5: Because all these little dampeners and feedback systems are important
• 28:15
  Speaker 5: to maintain normal homeostasis. So there's another molecule in our
• 28:22
  Speaker 5: body called growth hormone releasing hormone, GHRH. And that's our
• 28:27
  Speaker 5: own secretor. And some of the moralins, the samoralin, testamoralin, ipamoralin, hexamoralin,
• 28:33
  Speaker 5: they're in that family of the GHRH analogs. They look
• 28:37
  Speaker 5: and feel like a GHRH. So samoralin's older. I actually
• 28:41
  Speaker 5: don't use it. Some people still like it.
• 28:43
  Speaker 4: That's fine.
• 28:43
  Speaker 3: I just.
• 28:45
  Speaker 4: It would be a four out of five.
• 28:47
  Speaker 5: Because now these combos, this ipamoralin CJC 1295 is really
• 28:52
  Speaker 5: dialing it in for a lot of our people.
• 28:56
  Speaker 1: Perfect. Tiff, have you got any answers for me?
• 28:59
  Speaker 3: Yes, I do. It was 2013 that it became public
• 29:02
  Speaker 3: and it was the 2012 program. The main peptide was
• 29:08
  Speaker 3: thymus and beta-4. They have also listed AOD 9604, but
• 29:15
  Speaker 3: that didn't get ultimately charged for something due to the
• 29:20
  Speaker 3: legal status of that at the time. And then there
• 29:22
  Speaker 3: was other substances like colostrum, tribulus, and some vitamins and
• 29:30
  Speaker 3: IV treatments.
• 29:31
  Speaker 5: There you go.
• 29:32
  Speaker 2: Well, so what happened over here? Now, if I've fucked
• 29:36
  Speaker 2: some of this up, listeners, uh forgive me but so
• 29:40
  Speaker 2: this afl team under the guidance of.
• 29:44
  Speaker 1: Uh i think i think it was did my microphone
• 29:49
  Speaker 1: just go weird tiff no you did though under the.
• 29:53
  Speaker 2: Guidance of a well i'm always weird i've been weird
• 29:57
  Speaker 2: since the first fucking episode.
• 30:01
  Speaker 1: That's why Dr. Jeff comes back.
• 30:03
  Speaker 2: So anyway, they got in trouble big time for using
• 30:08
  Speaker 2: these peptides. And could you check on this for me?
• 30:13
  Speaker 2: Did Job Watson, J-O-B-E Watson, did he win the Brown
• 30:17
  Speaker 2: Low but have it taken away because he was part
• 30:21
  Speaker 2: of the program? So the Brown Low is like the MVP, Doc. Well,
• 30:26
  Speaker 2: it is the MVP essentially. Yeah, but that derailed their
• 30:32
  Speaker 2: whole season.
• 30:34
  Speaker 1: The coach got sacked.
• 30:36
  Speaker 2: The captain who I think won the MVP or the
• 30:39
  Speaker 2: equivalent for the competition got it taken away from him.
• 30:42
  Speaker 1: Is that correct, Tiff?
• 30:45
  Speaker 3: Yes, yep. He was ruled ineligible in November 2016.
• 30:51
  Speaker 1: Yeah, crazy.
• 30:53
  Speaker 2: And yeah, it was just this, I don't know, to
• 30:56
  Speaker 2: me it looked like a, a storm and a teacup,
• 31:00
  Speaker 2: like taking those things, would that have given, maybe it
• 31:05
  Speaker 2: would have a huge performance advantage. Would you call that
• 31:12
  Speaker 2: performance enhancing or recovery enhancing?
• 31:15
  Speaker 5: I would call it recovery enhancing, not performance enhancing. So we,
• 31:20
  Speaker 5: you know, we have professional athletes that use these all
• 31:22
  Speaker 5: the time. You know, a famous Aaron Rogers, you know,
• 31:29
  Speaker 5: but you know, we, we treat professional athletes at the
• 31:32
  Speaker 5: practice quietly and they get these and the trainers give them,
• 31:36
  Speaker 5: give them to them as well.
• 31:37
  Speaker 4: I mean, they're using them to recover.
• 31:39
  Speaker 5: If you hurt you, if you tore your ACL and
• 31:42
  Speaker 5: your knee and you had to have that surgically repaired,
• 31:45
  Speaker 5: is that not recovery enhancing?
• 31:47
  Speaker 4: Does that not bring you back?
• 31:49
  Speaker 2: Yeah.
• 31:49
  Speaker 4: So where do you draw the line here?
• 31:51
  Speaker 5: Why, why if thymus and beta four, which is a,
• 31:56
  Speaker 5: naturally occurring peptide in the body, give a little extra.
• 32:00
  Speaker 5: It's like testosterone. Is testosterone doping? Maybe you guys have
• 32:03
  Speaker 5: trouble getting it there, but these peptides are like small
• 32:07
  Speaker 5: fragment hormones.
• 32:08
  Speaker 4: In a way. Yes.
• 32:10
  Speaker 5: Yes.
• 32:11
  Speaker 2: It's like you think about, well, sleep is recovery enhancing, hydration,
• 32:20
  Speaker 2: quality food, calm, like... Everything is about like the whole
• 32:28
  Speaker 2: thing with training and preparing for an event or a
• 32:31
  Speaker 2: sport or a game is about performance enhancement. We all
• 32:36
  Speaker 2: want our players to be better, which is enhanced performance.
• 32:42
  Speaker 2: You know, win more games, run faster, jump higher, tackle harder,
• 32:46
  Speaker 2: hit harder, have better skills, execute more effectively under pressure.
• 32:51
  Speaker 1: Like all of this is improved performance.
• 32:55
  Speaker 2: It's literally, but yeah, it's trying to, and one of
• 33:00
  Speaker 2: the funny things that happens over here is, I'm sure
• 33:04
  Speaker 2: it happens over there, but I used to work in
• 33:06
  Speaker 2: the AFL system. I worked with an AFL team and
• 33:12
  Speaker 2: on our team and others, a player would get injured.
• 33:14
  Speaker 2: They'd come off. They've done something significant to their ankle,
• 33:19
  Speaker 2: for example.
• 33:21
  Speaker 1: And they can hardly wait there.
• 33:23
  Speaker 2: Like they're, you know, like they basically get carried off
• 33:27
  Speaker 2: by doctors or physios, you know, one arm over or
• 33:32
  Speaker 2: both arms over two shoulders. And then 10 minutes later,
• 33:35
  Speaker 2: they sprint back onto the ground like a fucking race horse.
• 33:39
  Speaker 1: I'm like, yeah, yeah. Well, if that's not performance enhancing,
• 33:46
  Speaker 1: you know what I'm saying? Yeah.
• 33:48
  Speaker 2: Yeah.
• 33:49
  Speaker 5: It's like they used to give people steroid shots in
• 33:53
  Speaker 5: their joints and get them back in the game. How
• 33:55
  Speaker 5: is that not performance enhancing? I mean, where do you
• 33:57
  Speaker 5: draw the line or recovery enhancing at least?
• 34:00
  Speaker 4: Yeah.
• 34:00
  Speaker 5: So the problem is the line is drawn in this
• 34:02
  Speaker 5: strange way, hypocritical way. It's just not it's not logical.
• 34:08
  Speaker 5: And these are natural things. I mean, they were discovered.
• 34:12
  Speaker 5: Most of these peptides were discovered by. by uh you
• 34:15
  Speaker 5: know looking at organ meats from animals like okay let's
• 34:19
  Speaker 5: eat let's eat a thymus and see what happens you know.
• 34:22
  Speaker 2: Oh god let's have some bull testicles on toast tiff
• 34:27
  Speaker 2: and let's see what that does to us with a
• 34:28
  Speaker 2: little bit of mayo that's how.
• 34:31
  Speaker 4: You get your torn brain that's where it comes from.
• 34:33
  Speaker 2: Yeah let's get those pubes out first though tiff oh
• 34:37
  Speaker 2: you can do that.
• 34:40
  Speaker 1: Someone will do it. All right.
• 34:43
  Speaker 2: There's a couple I don't even know. I've never even
• 34:45
  Speaker 2: heard of. So I'm going to skip them because I
• 34:46
  Speaker 2: don't think. Let's go to, is it epitalon?
• 34:52
  Speaker 4: Epitalon, it's fine.
• 34:55
  Speaker 5: So this is an extract from the pineal gland, another
• 34:59
  Speaker 5: gland that shrivels up with age. And it's known for
• 35:03
  Speaker 5: improving telomere length and thereby resetting the cells to a
• 35:10
  Speaker 5: more youthful state. So it's used mostly in the anti-aging circles.
• 35:15
  Speaker 5: It also can restore some melatonin production in your own
• 35:19
  Speaker 5: pineal gland and assist with deep restorative sleep.
• 35:24
  Speaker 1: Yes, right.
• 35:26
  Speaker 2: Okay, so here it says longevity, circadian rhythm, sleep and
• 35:30
  Speaker 2: cellular aging, a legendary longevity world record. compound but the
• 35:36
  Speaker 2: human evidence is nowhere near the strength of the claims
• 35:39
  Speaker 2: uh one out of five what would you give it
• 35:42
  Speaker 2: what's your score.
• 35:43
  Speaker 5: I i give it a four out of five only
• 35:45
  Speaker 5: because it's not something i reach for often unless someone
• 35:48
  Speaker 5: says hey doc what are the best peptides for longevity
• 35:50
  Speaker 5: or to help me sleep you know i'm i'm reaching
• 35:53
  Speaker 5: for glps and and muscle you know growth hormones secretogogs
• 35:57
  Speaker 5: muscle gain i'm looking for mitochondrial repair things like that.
• 36:01
  Speaker 2: Yes Yeah, there was a doctor who was working with
• 36:07
  Speaker 2: the club that we were talking about before.
• 36:10
  Speaker 1: His name is Dr. Robin Wilcourt. I actually think he
• 36:14
  Speaker 1: now lives in Vegas. He may not. I think he
• 36:18
  Speaker 1: definitely is in the States.
• 36:20
  Speaker 2: He basically got ran out of Australia because he was
• 36:24
  Speaker 2: prescribing peptides. And yeah, I used to train him. And
• 36:32
  Speaker 2: he was, yeah, I don't know. I mean, he would
• 36:37
  Speaker 2: be probably early 80s now. But even back then in
• 36:40
  Speaker 2: his early 70s, his cognitive function was like a 20-year-old
• 36:46
  Speaker 2: and he was in.
• 36:48
  Speaker 1: Great shape, like great shape.
• 36:51
  Speaker 2: So one of the things that's been used quite a
• 36:54
  Speaker 2: lot over here, Doc, officially or unofficially is AOD 9604.
• 36:59
  Speaker 2: I'll give you their blurb, then you give me yours.
• 37:02
  Speaker 2: Fat metabolism and reduction of body fat.
• 37:05
  Speaker 1: Well, they seem to go together.
• 37:08
  Speaker 2: Popular in body composition circles, much less convincing clinically than
• 37:15
  Speaker 2: GLP-1 drugs.
• 37:16
  Speaker 1: Their score is a one to two.
• 37:19
  Speaker 5: Yeah, I'd give it a three and a half out
• 37:23
  Speaker 5: of five, only because there is less information on this one.
• 37:27
  Speaker 4: We do use it. for people who.
• 37:29
  Speaker 5: Might already be at the right body composition, but they
• 37:32
  Speaker 5: have a little extra fat they want to burn maybe
• 37:34
  Speaker 5: before some summer bathing suit weather or bodybuilding.
• 37:39
  Speaker 4: Competition or something like that.
• 37:41
  Speaker 5: There is published evidence that it could be useful as
• 37:45
  Speaker 5: part of a joint to help joints recover if it's
• 37:50
  Speaker 5: put into the joint. And, you know, I do a
• 37:52
  Speaker 5: lot of procedures like that. So we offer it as
• 37:54
  Speaker 5: an add-on for joint and spine procedures.
• 37:58
  Speaker 1: Okay, perfect. Tiff, is my mic okay?
• 38:01
  Speaker 3: It is fabulous.
• 38:03
  Speaker 2: Sorry, everyone, having microphone issues today. It's either my ears
• 38:06
  Speaker 2: or the mic. I can't tell. Something's fucked. Let's do
• 38:11
  Speaker 2: a couple more. Then I want to hear about your stack.
• 38:15
  Speaker 4: Yeah.
• 38:17
  Speaker 1: So let's go with, I've never heard of this. Maybe
• 38:21
  Speaker 1: you haven't. I'm sure you have. KPV.
• 38:23
  Speaker 4: Yep, Tiff.
• 38:26
  Speaker 1: Anti-inflammatory effects, gut and skin applications.
• 38:31
  Speaker 2: An interesting fragment of AMSH that's become popular in the
• 38:37
  Speaker 2: gut inflammation conversation.
• 38:39
  Speaker 1: They give it a one.
• 38:41
  Speaker 2: Yep.
• 38:42
  Speaker 5: So like most peptides, it's a fragment of another molecule
• 38:46
  Speaker 5: that occurs in our body. This case, alpha melanocyte stimulating hormone, AMSH.
• 38:53
  Speaker 4: So it is.
• 38:55
  Speaker 5: a three amino acid peptide and amino acids have a
• 38:59
  Speaker 5: one letter code. And some of the peptides are named
• 39:02
  Speaker 5: by that code. In this case, KPV represents the three
• 39:06
  Speaker 5: amino acids in order that make this one up. So
• 39:09
  Speaker 5: it's named by the code. It doesn't have its own
• 39:11
  Speaker 5: special name. So it is anti-inflammatory. We use it in
• 39:15
  Speaker 5: our recovery and anti-inflammatory stacks. It's part of my stack
• 39:19
  Speaker 5: you'll hear about.
• 39:20
  Speaker 4: Yeah.
• 39:21
  Speaker 2: Great.
• 39:22
  Speaker 1: How, how many, What do you think, I.
• 39:27
  Speaker 2: Mean, you can't know this, but- would 10% of Americans
• 39:31
  Speaker 2: be using peptides? Would it be two? Would it be 30? Like,
• 39:35
  Speaker 2: what would it be close to?
• 39:38
  Speaker 5: Well, I read on social media, I don't know how
• 39:41
  Speaker 5: accurate it is, that something like one in eight to
• 39:43
  Speaker 5: one in 10 Americans are using a GLP. Wow. And
• 39:49
  Speaker 5: that's likely. America is incredibly fat. It's just the way
• 39:57
  Speaker 5: we're fed.
• 39:57
  Speaker 2: There's the title for the show, Tiff. Jot it down.
• 40:00
  Speaker 2: America is incredibly fat. Spoken and authorized by Dr.
• 40:04
  Speaker 1: Jeff Gross.
• 40:05
  Speaker 4: It's just the way we're fed. Yeah.
• 40:07
  Speaker 5: So I think that that could be true. I mean,
• 40:12
  Speaker 5: that's why... Reddit True Tide will be a trillion dollar drug.
• 40:17
  Speaker 4: For Eli Lilly. So my stock pick is Eli Lilly.
• 40:24
  Speaker 5: Wow.
• 40:25
  Speaker 1: There you go. You're getting body stuff. You're getting financial
• 40:27
  Speaker 1: investment stuff.
• 40:28
  Speaker 2: You're getting the odd opinion and the odd judgment on
• 40:33
  Speaker 2: an entire nation.
• 40:34
  Speaker 1: America is bad. You're welcome. You don't get that anywhere else.
• 40:38
  Speaker 4: Fuck it.
• 40:38
  Speaker 1: Just here. Just here.
• 40:40
  Speaker 2: All right. So what is the what is the doctor
• 40:43
  Speaker 2: who's in the middle of all of this conversation and
• 40:47
  Speaker 2: prescribing and supporting and helping patients?
• 40:49
  Speaker 1: What does he take? What does that guy take?
• 40:53
  Speaker 4: Glad you asked. So I take retratrutide low dose once
• 40:58
  Speaker 4: a week.
• 40:59
  Speaker 5: I'm at a weight and body composition that's really good,
• 41:04
  Speaker 5: although I'm always trying to gain a little extra muscle.
• 41:08
  Speaker 5: So I've got my fat down to 12% and I'm
• 41:13
  Speaker 5: content there. And I just need to get that lean
• 41:16
  Speaker 5: muscle mass up, which, which means my weight will go
• 41:19
  Speaker 5: up because I don't want to lose any more, anything else.
• 41:23
  Speaker 4: I want to just gain muscle. So I back that.
• 41:25
  Speaker 4: So people get freaked out. Hey, I'm on a road
• 41:27
  Speaker 4: to tide. I'm doing all this muscle stuff and I'm
• 41:29
  Speaker 4: gaining weight.
• 41:30
  Speaker 5: Well, if we had a body composition analysis and we
• 41:32
  Speaker 5: would know what kind of weight you're gaining, if it's muscle,
• 41:34
  Speaker 5: you should smile about it.
• 41:36
  Speaker 4: So I take that.
• 41:38
  Speaker 5: Not just for body comp, but for reduction of fat
• 41:42
  Speaker 5: in the liver, for reducing the HbA1c, improving insulin sensitivity, etc.
• 41:48
  Speaker 5: It also drives down your hunger, which is nice. So
• 41:51
  Speaker 5: I'm not reaching for a bag of chips. You call
• 41:53
  Speaker 5: them chips or crisps over there?
• 41:55
  Speaker 1: Yeah, chips. Okay. Chips.
• 41:58
  Speaker 5: And then for no reason. Those are empty calories. So
• 42:03
  Speaker 5: I also take with varying amounts and needs... a recovery
• 42:09
  Speaker 5: stack called CLOW, K-L-O-W. It has four peptides mixed together
• 42:15
  Speaker 5: in one vial that work well together. And BPC-157 is
• 42:19
  Speaker 5: in there. TB-500 is in there. KPV, which we just
• 42:24
  Speaker 5: talked about, is in there. And the copper binding peptide, GHK-CU. GHK,
• 42:31
  Speaker 5: that same kind of lettering code represents another tripeptide, three
• 42:36
  Speaker 5: amino acids. These three bind copper and deliver it to
• 42:40
  Speaker 5: places in our cell where we need it. For example,
• 42:42
  Speaker 5: collagen production. So you can see how that's important in
• 42:46
  Speaker 5: healing and recovery. Those four, if used well, are incredible.
• 42:53
  Speaker 5: So I use them when I know I'm going to
• 42:55
  Speaker 5: be overdoing it. So we take the grandkids to Disneyland.
• 43:00
  Speaker 5: I'm going to be walking 20,000 steps that day, three
• 43:03
  Speaker 5: days in a row from 7 a.m.
• 43:05
  Speaker 4: To midnight. I'm taking.
• 43:07
  Speaker 5: I'm taking a hefty dose of Clow that evening. So
• 43:11
  Speaker 5: I can do that for three days in a row.
• 43:13
  Speaker 5: And by the end of the third day, my kids
• 43:15
  Speaker 5: are saying, oh, can we sit down?
• 43:17
  Speaker 4: Can we put our feet up? I'm tired. I'm not. Yes. Also,
• 43:22
  Speaker 4: I had a few days ago, I pulled or tweaked
• 43:26
  Speaker 4: something in the back of my shoulder. I'm like, oh, great.
• 43:28
  Speaker 5: There I am. Old guy got a rotator cuff tear
• 43:30
  Speaker 5: or something. I took a very large slug of Clow
• 43:34
  Speaker 5: two nights ago. I took a medium slug last night.
• 43:38
  Speaker 5: And I'm probably 90% better already. That's not how I
• 43:41
  Speaker 5: would normally recover from.
• 43:44
  Speaker 4: Something like that.
• 43:45
  Speaker 1: That's crazy. That's crazy.
• 43:47
  Speaker 4: Yeah. Those are two. I got more when you're ready.
• 43:54
  Speaker 1: Oh, got it.
• 43:56
  Speaker 4: So at times, I will take something called PT-141.
• 43:59
  Speaker 5: Yeah.
• 43:59
  Speaker 4: This is a fragment of what's called, um, uh, Milano's, uh,
• 44:12
  Speaker 4: hold on a second. Let me think about it.
• 44:14
  Speaker 5: It's, it's Milano 10, two and Milano 10, two stimulates,
• 44:18
  Speaker 5: which I've tried before as well, stimulates you to tan
• 44:22
  Speaker 5: to pigment, but it has a side effect because a
• 44:25
  Speaker 5: fragment of it causes you to have an increased libido
• 44:29
  Speaker 5: and blood flow to your genitals, both for men and women.
• 44:33
  Speaker 5: So you can just take the PT141 fragment and have,
• 44:38
  Speaker 5: you know, high school-like thoughts and activities.
• 44:44
  Speaker 1: Let me just, can you just spell, what the fuck
• 44:47
  Speaker 1: do I need that for, Tiff? Fucking hell.
• 44:52
  Speaker 2: I've been buying my left-hand dinner since the 80s, so,
• 44:55
  Speaker 2: you know.
• 44:59
  Speaker 1: Oh, that's not true, everyone.
• 45:00
  Speaker 3: Your left hand might appreciate it then.
• 45:02
  Speaker 4: Yeah.
• 45:05
  Speaker 1: Date night let's not use that in a promo.
• 45:10
  Speaker 3: Melissa please do.
• 45:13
  Speaker 5: Uh keep going doc um let's see what else so
• 45:17
  Speaker 5: you know i have uh on a routine basis that's
• 45:22
  Speaker 5: my my stack i have tried others i've tried the
• 45:26
  Speaker 5: sleep peptide dsip delta sleep inducing.
• 45:28
  Speaker 4: Peptide It gets you into that deeper sleep wave. I'm
• 45:32
  Speaker 4: really good.
• 45:32
  Speaker 5: I take my melatonin. You and I have talked about
• 45:35
  Speaker 5: melatonin many times, and I can have deep sleep. Epitalon
• 45:41
  Speaker 5: is another way to get your melatonin up. We talked
• 45:43
  Speaker 5: about that earlier. There are some mitochondrial peptides I've used
• 45:48
  Speaker 5: and we have great success with generally. And mitochondria, you know,
• 45:52
  Speaker 5: the CEO of the cell, the battery of the cell,
• 45:54
  Speaker 5: not just the powerhouse.
• 45:56
  Speaker 4: So we see a.
• 45:57
  Speaker 5: Lot of people come in with these energy depletions, low energy,
• 46:02
  Speaker 5: not sleeping well, don't want to exercise, don't want anything done,
• 46:07
  Speaker 5: brain fog. Turns out a lot of them have different things.
• 46:09
  Speaker 5: They have a longstanding infection. They have suffered long COVID
• 46:16
  Speaker 5: or something like that.
• 46:17
  Speaker 4: And the COVID.
• 46:18
  Speaker 5: Spike protein is known to damage the membrane of the mitochondria.
• 46:22
  Speaker 5: So the membrane is your battery seal. You have to
• 46:25
  Speaker 5: seal the battery so you can have that differential in charge.
• 46:28
  Speaker 5: So we use a peptide called SS31, which is also
• 46:32
  Speaker 5: approved for marketing claims by the FDA for a particular disease.
• 46:35
  Speaker 5: It can be used off-label to help restore the inner membrane.
• 46:39
  Speaker 4: We use it for a month.
• 46:40
  Speaker 5: And then we follow that up with another mitochondrial peptide
• 46:44
  Speaker 5: called MOTS-C, which that you release yourself when you exercise.
• 46:49
  Speaker 5: It's called a myokine or an exokine. It's why when
• 46:52
  Speaker 5: you use your muscles, the rest of your body benefits.
• 46:55
  Speaker 5: It releases that and gets into the.
• 46:56
  Speaker 4: Rest of the body.
• 46:57
  Speaker 5: Well, you can take some of that. Once your battery
• 47:00
  Speaker 5: is sealed, you use the MOTC to charge your battery.
• 47:02
  Speaker 5: Then your mitochondria are working better. Assuming that's your main problem,
• 47:06
  Speaker 5: could be other things too. We've seen amazing turnarounds. And Tiff,
• 47:12
  Speaker 5: we're using that to get people off ADHD drugs. Right.
• 47:18
  Speaker 1: Wow.
• 47:19
  Speaker 2: Maybe you need a five-minute chat.
• 47:23
  Speaker 1: Always fascinating.
• 47:24
  Speaker 3: Can I ask one question?
• 47:26
  Speaker 1: Yeah, you can ask three.
• 47:28
  Speaker 4: I was thinking, Dr.
• 47:29
  Speaker 3: Jeff, given now what we have available, which is awesome,
• 47:35
  Speaker 3: and the access to that information, but also the misinformation
• 47:41
  Speaker 3: and the impact of things like ChatGBT and the influence
• 47:45
  Speaker 3: that that has on understanding and I guess what we believe,
• 47:52
  Speaker 3: do you think broadly we are better off or in
• 47:57
  Speaker 3: no better position?
• 47:59
  Speaker 1: Do the pros outweigh the cons?
• 48:02
  Speaker 5: Well, I advocate that if you, you know, peptides are
• 48:06
  Speaker 5: an amazing tool, but you have to have someone coaching you,
• 48:09
  Speaker 5: looking over your shoulder with experience, maybe with some kind
• 48:12
  Speaker 5: of diploma would help. So do it right. Make sure
• 48:17
  Speaker 5: you get it from a vetted source, certificate of analysis.
• 48:20
  Speaker 4: The stuff is legit. It's not from Timu. And then
• 48:25
  Speaker 4: we're way better off.
• 48:26
  Speaker 5: We're way better off because a lot of these trump,
• 48:30
  Speaker 5: pharmaceuticals and surgeries. And listen, I do, I do joint procedures.
• 48:35
  Speaker 5: We do cartilage regenerative procedures and I do an injection procedure.
• 48:39
  Speaker 5: So we have people call us, Hey, I got a
• 48:41
  Speaker 5: knee problem.
• 48:42
  Speaker 4: I don't want surgery. Can you help me out?
• 48:43
  Speaker 5: Let's take a look. Let's get an MRI. Let's, let's,
• 48:46
  Speaker 5: you know, get you going in the meantime. Are you
• 48:49
  Speaker 5: interested in peptides?
• 48:49
  Speaker 2: Yeah.
• 48:50
  Speaker 4: Let's give it a try.
• 48:50
  Speaker 1: Okay.
• 48:51
  Speaker 5: We get back on the phone, you know, a month later, okay,
• 48:54
  Speaker 5: I'm following up on those peptides, but we're, you know,
• 48:57
  Speaker 5: seeing how if you get ready for that procedure, I
• 48:59
  Speaker 5: got your MRI here. And they're like, doc, I don't
• 49:01
  Speaker 5: need a procedure. Peptide took care of it.
• 49:04
  Speaker 3: Wow.
• 49:05
  Speaker 4: So it's, it's killing my business, but I like it.
• 49:10
  Speaker 1: Well, it's a.
• 49:10
  Speaker 2: Noble way to go down with a ship. You know,
• 49:13
  Speaker 2: I got no dough, my career's fucked, but I helped
• 49:16
  Speaker 2: a lot of people.
• 49:17
  Speaker 1: That could be the title too, Tiff.
• 49:19
  Speaker 4: That could be the title.
• 49:21
  Speaker 1: Doc, tell people how to connect with you or find you.
• 49:25
  Speaker 5: Check us out at recelebrate, R-E-C-E-L-L-E-B-R-A-T-E, Instagram, TikTok, Facebook, LinkedIn, web, recelebrate.com,
• 49:39
  Speaker 5: Reach out, tell us what you're interested in, what you
• 49:41
  Speaker 5: want to talk about, and we'll find time, even if
• 49:44
  Speaker 5: you're in a completely different time zone, like the You
• 49:47
  Speaker 5: Project is.
• 49:48
  Speaker 2: Yes, yes. We're in 1942, but fuck it's good back here.
• 49:53
  Speaker 2: I hope the war ends soon.
• 49:56
  Speaker 3: I can't wait to see that incident scandal play out.
• 50:01
  Speaker 1: Yes, yeah, yeah. And wait for electric cars and typewriters.
• 50:06
  Speaker 1: They're going to be huge. I think typewriters are here,
• 50:10
  Speaker 1: aren't they? Yes, they are. See you next time, everyone.