Latest / Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology
Intrathecal Mesenchymal Stem Cells in Progressive MS: The SMART-MS Trial
This randomized, double-blind study investigated the potential for autologous mesenchymal stem cells (MSCs) to repair neurological damage in patients with progressive multiple sclerosis. Using an intrathecal administration route to bypass the blood-brain barrier, researchers monitored nerve conduction speeds and brain volume changes over a year. The results failed to demonstrate a significant neuroregenerative effect, as the primary measures of electrical signal latency showed no improvement compared to the placebo group. While cerebrospinal fluid proteomics suggested some anti-inflammatory…
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