Latest / Wellness, Actually with Emily Oster & Perry Wilson, MD / What's the deal with the sun?
Transcript
- 0:01Speaker 1: Emily, the Sun is really big. Did you know that
- 0:07Speaker 1: the Sun is bigger than all the planets in the
- 0:11Speaker 1: Solar System?
- 0:12Speaker 2: I did know that, very yes, But say more about
- 0:15Speaker 2: how big the Sun.
- 0:17Speaker 1: Nine percent of the mass in the Solar System is
- 0:19Speaker 1: in the Sun. It's that big. It's almost everything. Everything
- 0:22Speaker 1: else is a rounding error. And Okay, this doesn't have
- 0:25Speaker 1: to do with wellness, but I wanted to give some
- 0:28Speaker 1: fun sun facts before we got into our episode about
- 0:32Speaker 1: the Sun. And one thing that kept coming across was that,
- 0:36Speaker 1: you know, you could fit one point three million earths
- 0:39Speaker 1: inside the Sun. That's how big it is. That's a
- 0:42Speaker 1: lot of earths, and that's all over the place. But
- 0:45Speaker 1: I was like, wait, is that really true? Because it's
- 0:48Speaker 1: not like the earths would just sit there, do you
- 0:51Speaker 1: know what I mean?
- 0:52Speaker 2: I always sort of imagine it was like if the
- 0:54Speaker 2: Sun were like a jar and you put and the
- 0:57Speaker 2: Earth was a gumball. That means it's like a point
- 1:00Speaker 2: three million gumballs? Is that right?
- 1:01Speaker 1: But do you know what happens if you put a
- 1:04Speaker 1: million earths together? Is like they all have gravity and
- 1:06Speaker 1: they start crushing in on each other and and it
- 1:09Speaker 1: turns out again, Okay, right now where physics actually it
- 1:13Speaker 1: turns out that as you add earths into a big ball,
- 1:19Speaker 1: these really interesting things happen. So after three hundred and
- 1:22Speaker 1: thirty three earths, adding additional earths actually makes the volume
- 1:28Speaker 1: of the Earth's smaller. Three hundred and thirty three earths,
- 1:32Speaker 1: because the Earth is made primarily of iron. Is when
- 1:35Speaker 1: gravity can pull the atoms together, or the nuclei of
- 1:39Speaker 1: the atoms together, even though the electrons are trying to
- 1:42Speaker 1: fight against it, right, so they like is actually getting
- 1:44Speaker 1: denser and denser and.
- 1:45Speaker 2: Sucking it in.
- 1:46Speaker 1: Okay, by the time you're three hundred and thirty four earths,
- 1:49Speaker 1: the thing is just getting smaller. When you get to
- 1:52Speaker 1: three hundred and thirty three thousand earths, that exceed gravity,
- 1:57Speaker 1: exceeds the electron degeneracy pressure, and all those earths form
- 2:01Speaker 1: a white dwarf star. So it just sits there being
- 2:06Speaker 1: a white dwarf star about the size of the Earth.
- 2:11Speaker 1: So three hundred and thirty three thousand earths and one
- 2:14Speaker 1: earth about.
- 2:15Speaker 2: The size of one Earth, but very hot.
- 2:18Speaker 1: If you took the one point three million earths that
- 2:21Speaker 1: the Internet says you can stick inside the sun and
- 2:24Speaker 1: actually put them in the sun, you would get a
- 2:27Speaker 1: black hole, and the size of that black hole would
- 2:31Speaker 1: be eleven five hundred meters across, about the size of
- 2:35Speaker 1: New Haven, Connecticut city limits.
- 2:39Speaker 2: That is totally fascinating, and I think it's a good
- 2:41Speaker 2: open because a lot of people might be wondering, like, hey,
- 2:46Speaker 2: use episodes about the sun? What is the sun? You know?
- 2:48Speaker 2: And we'd like to abide some information at the top.
- 2:51Speaker 2: And I also thought about a way to provide people information.
- 2:53Speaker 2: And you went with science and I went with they
- 2:56Speaker 2: might be giants. And so let me just give you
- 2:59Speaker 2: a little clip in song from the best song ever
- 3:04Speaker 2: written about the Sun by Day Maybe Giants. Sun is
- 3:08Speaker 2: a massive incandescent GASA gigantic nuclear furnace where hydrogen is
- 3:13Speaker 2: fused into heale at temperatures of millions of degrees. It
- 3:17Speaker 2: goes on from there. And if you have any children
- 3:19Speaker 2: who are interested in the sun, I highly recommend that
- 3:21Speaker 2: you have that them listen to that song instead of
- 3:24Speaker 2: listening to Perry's description, even though I did think it
- 3:27Speaker 2: was very interesting. I'm Emily Aster, I'm an economist and
- 3:34Speaker 2: a data expert, and.
- 3:35Speaker 1: I'm Perry Wilson, I'm a medical doctor.
- 3:38Speaker 2: It's Thursday, July thirtieth, twenty twenty six. And this is wellness.
- 3:41Speaker 1: Actually, because you're getting a staggering amount of health and
- 3:45Speaker 1: wellness information nowadays from every source imaginable, and some of
- 3:49Speaker 1: it is awesome and some.
- 3:51Speaker 2: Of it is well actually both Fortunately we are both
- 3:56Speaker 2: people who know how to read studies, how to parse
- 3:59Speaker 2: the data, and can tell you what's worth thinking about
- 4:02Speaker 2: and what you can safely ignore.
- 4:04Speaker 1: But before we dig in, a note that this podcast
- 4:06Speaker 1: is for educational purposes and should not be construed as
- 4:09Speaker 1: medical advice. We don't know your unique situation, so talk
- 4:12Speaker 1: to your doctor for personal health decisions.
- 4:15Speaker 2: Here comes the sun this week we're asking what's the
- 4:18Speaker 2: deal with the sun? Perry, and I will give the
- 4:21Speaker 2: official smash or pass? Do we even need the sun anyway?
- 4:25Speaker 2: And then we'll get to your questions of the wo
- 4:26Speaker 2: hot But first let's do the health news round up
- 4:30Speaker 2: after the break. And now let's do the health news
- 4:45Speaker 2: of the week. My first question for you, Perry, I
- 4:48Speaker 2: noticed that the cardiologists have finally come out in support
- 4:54Speaker 2: of one of my more central personal habits, which is
- 4:58Speaker 2: consumption of coffee. And the cardio biologists of America have
- 5:01Speaker 2: said coffee's great. Why did they say that? Now?
- 5:06Speaker 1: I guess people were kind of down on cardiology and
- 5:09Speaker 1: they were like, you guys are such wet blankets, always
- 5:12Speaker 1: telling us not to drink alcohol or like eat fatty
- 5:15Speaker 1: foods or whatever, and they needed to get some street creds.
- 5:19Speaker 1: So the American Heart Association has released a formal document
- 5:22Speaker 1: on caffeine and the cardiovascular risks and benefits, and it
- 5:27Speaker 1: goes through decades of research into the substance, but I'll
- 5:32Speaker 1: summarize in saying they basically gave a thumbs up to coffee,
- 5:36Speaker 1: to ingesting caffeine in the form of coffee, noting across
- 5:39Speaker 1: several studies that there's stuff in coffee that might be
- 5:42Speaker 1: healthy even beyond caffeine, and sort of are equivocal on
- 5:47Speaker 1: caffeine supplemented beverages and gels and energy drinks and things
- 5:51Speaker 1: like that. But overall, some of the sort of myths
- 5:53Speaker 1: that got dispelled in this document. Number one that was
- 5:56Speaker 1: surprising to me even was they talk about generally coffee
- 6:01Speaker 1: being less likely to promote atrial fibrillation, the most common
- 6:05Speaker 1: cardiac arrhythmia. We always sort of counsel people with a
- 6:08Speaker 1: fib or we used to counsel people with aphib like, oh,
- 6:11Speaker 1: don't avoid coffee if you're trying to stay out of
- 6:13Speaker 1: aphib AJ says not true. In fact, the current guidelines
- 6:18Speaker 1: advise specifically against telling people not to drink coffee if
- 6:21Speaker 1: they have atrial fibrillation. Some other interesting stuff. They note
- 6:25Speaker 1: a randomized controlled trial which showed that coffee increases LDL
- 6:29Speaker 1: cholesterol that's the bad cholesterol, but not if you pass
- 6:32Speaker 1: it through a paper filter. There's a substance in coffee
- 6:37Speaker 1: that raises cholesterol but gets absorbed into paper filters. So
- 6:40Speaker 1: maybe that's an argument against French presses, although that is
- 6:43Speaker 1: a nice form of coffee that I like. I love
- 6:47Speaker 1: finding things, though Emily like I have a list of
- 6:50Speaker 1: three things. I wonder if you can guess these. There
- 6:52Speaker 1: are three things in life where that are pleasurable, and
- 6:55Speaker 1: science also tells you that they're good for you. Like
- 6:58Speaker 1: most things, it's like, ah, you know, it's not that pleasurable,
- 7:02Speaker 1: but you got to do it. Eat your broccoli, right,
- 7:03Speaker 1: So coffee is one of them. I have two more.
- 7:07Speaker 2: What are your other two?
- 7:08Speaker 1: I'm curious what you're two? So so the only the
- 7:10Speaker 1: only other two I've been able to think of our
- 7:12Speaker 1: sleep and sex. Coffee, sleep and sex. That's it. Everything else.
- 7:17Speaker 1: If it feels good, it's bad for you.
- 7:20Speaker 2: Yeah that sounds that sounds right.
- 7:21Speaker 1: I mean people be like, oh, exercise, Like I love exercise. No,
- 7:26Speaker 1: you don't, come on, I do know.
- 7:28Speaker 2: I will tell you I do actually love exercise.
- 7:30Speaker 1: It's the endorphins. Let's say, but if you could just
- 7:33Speaker 1: lie around eating doritos, no I would.
- 7:35Speaker 2: I totally would not do that. But I will go
- 7:38Speaker 2: with yeah, yeah, coffee, sleep, sex, and exercise on my head.
- 7:41Speaker 2: Here was what I will say about this coffee thing.
- 7:44Speaker 2: Very nice. I broadly think that there's a lot of
- 7:47Speaker 2: good stuff in this report. I will say I am
- 7:51Speaker 2: always very frustrated that these reports seem to rely on
- 7:56Speaker 2: both observational and randomized data and not like this distinguish them.
- 8:01Speaker 2: I mean, coffee makes you Live Forever is like a
- 8:03Speaker 2: standard headline that shows up in a lot of coverage
- 8:07Speaker 2: of garbage observational studies. These guys like, some of what
- 8:11Speaker 2: they're saying is based on randomized trials, some is based
- 8:13Speaker 2: on observational data. I just wish they would talk about
- 8:16Speaker 2: the randomized trials, like, here are the things we actually
- 8:19Speaker 2: know and here are some you know, associations which you
- 8:21Speaker 2: should take with a grain of salt. And I think
- 8:23Speaker 2: they don't do that because they don't have the same
- 8:25Speaker 2: skepticism that I do for observational data. But anyway, that's
- 8:29Speaker 2: my problem.
- 8:31Speaker 1: I hear you, and that skepticism comes through loud and clear.
- 8:34Speaker 1: Let's move on to a rather bleak record that we have.
- 8:43Speaker 1: There have been more measles cases reported in the United
- 8:46Speaker 1: States in the last two years than in all the
- 8:50Speaker 1: years from two thousand through twenty twenty four combined. Emily,
- 8:56Speaker 1: what's going on with measles?
- 8:58Speaker 2: Yeah, there's some actually other ways to look at that data,
- 9:01Speaker 2: which I think are even more disturbing. Like there was
- 9:04Speaker 2: a single week in January when there were more measles
- 9:07Speaker 2: cases than all, like than the yearly count for all
- 9:10Speaker 2: but a few years in the past twenty years. So
- 9:12Speaker 2: we're having a very unusual outbreak set of measles. What
- 9:17Speaker 2: is happening is pretty clear. We are in a period
- 9:20Speaker 2: of increased vaccine hesitancy. Vaccine rates have been going down
- 9:24Speaker 2: for a long period of time, and that means we
- 9:27Speaker 2: have a lot of kids who are unvaccinated. Measles is
- 9:30Speaker 2: super super super contagious. They are not. Is something like
- 9:34Speaker 2: twelve to fifteen, which means any individual person with measles
- 9:38Speaker 2: can spread it to is expected to spread it to
- 9:40Speaker 2: twelve to fifteen other people if everyone was unvaccinated. That's way, way,
- 9:45Speaker 2: way higher than almost any other viral illness that we
- 9:47Speaker 2: talk about. And so it's just.
- 9:49Speaker 1: Yea, it is like one point five.
- 9:51Speaker 2: Yeah, it was just super super contagious. And if you
- 9:53Speaker 2: have a school where fifty percent of the kids are vaccinated,
- 9:57Speaker 2: which we do have some of, then one kids get meels,
- 10:00Speaker 2: A lot of people get measles, and so you know, look,
- 10:03Speaker 2: I mean there is an obvious solution for this. It
- 10:06Speaker 2: is for more people to get vaccinated. It's not rocket science.
- 10:09Speaker 2: We have a great, great way to fix this problem.
- 10:13Speaker 2: Vaccine hesitancy continues to rise. The CDC currently features a
- 10:19Speaker 2: website that says that autism has something like vaccines have
- 10:23Speaker 2: not been shown not to cause autism or something incredibly misleading.
- 10:28Speaker 2: That is totally wrong and the whole thing is very frustrating.
- 10:32Speaker 1: Yeah, it is. If you look at vaccination rates nationwide
- 10:37Speaker 1: for measles, they look okay, you know, ninety three percent
- 10:40Speaker 1: of kindergarteners or something like that. But one of the
- 10:43Speaker 1: problems in infectious disease epidemiology is that infectious disease has
- 10:48Speaker 1: spread locally. And so the problem is it's not ninety
- 10:51Speaker 1: three percent everywhere. It's one hundred percent in some places,
- 10:54Speaker 1: and it's eighty percent, seventy five percent even lower in
- 10:57Speaker 1: other places, and and those tend to cluster together, which
- 11:01Speaker 1: is why you see all these outbreaks. And yes, the
- 11:04Speaker 1: CD despite, I will say officially, the HHS says, the
- 11:08Speaker 1: Health and Human Services Department says, quote vaccination is the
- 11:12Speaker 1: best defense against measles. Okay, folks, So there you go.
- 11:14Speaker 1: That's their official word. But of course they also put
- 11:17Speaker 1: up this website and yeah, Emily, it says basically, it's like,
- 11:21Speaker 1: while there's no evidence that vaccines cause autism, there's no
- 11:24Speaker 1: good evidence that they don't cause autism. Which, hey, even
- 11:28Speaker 1: that's not true, like we have plenty of studies showing
- 11:30Speaker 1: no link so much and a much proving a negative.
- 11:34Speaker 1: Like you can always kind of say that. It's like
- 11:36Speaker 1: it's like, you know, I can't prove to you that
- 11:40Speaker 1: there's not a whale orbiting the earth right now, like
- 11:43Speaker 1: there could be like it's possible we just didn't detect
- 11:46Speaker 1: it yet, right like, which is just such wishy washy stuff.
- 11:49Speaker 1: No medical science is ever going to be one hundred
- 11:51Speaker 1: percent on anything, but we're actually pretty darn close when
- 11:55Speaker 1: it comes to vaccination totally.
- 11:57Speaker 2: All right. Well, you know, perhaps people will respond to
- 12:02Speaker 2: the existence of measles by vaccinating a higher rates, which
- 12:05Speaker 2: we do see happen. So I guess that's chose a
- 12:07Speaker 2: self limiting aspect. Your potentially last thing we wanted to
- 12:10Speaker 2: talk about was peptides. The FDA is back for your peptides.
- 12:16Speaker 2: If you are a listener after this show, please go
- 12:18Speaker 2: back and listen to our episode on pep pides. And
- 12:20Speaker 2: one of the things we said there was you can't
- 12:23Speaker 2: get peptides in America. You have to get them from
- 12:26Speaker 2: overseas manufacturers. The FDA heard us and they were like, oh,
- 12:30Speaker 2: we should make those.
- 12:32Speaker 1: Why are we outsourcing all? Are we outsourcing improvens to China?
- 12:37Speaker 1: As an FDA panel has voted to authorize several peptides
- 12:43Speaker 1: which people may have heard of, including on our prior episode,
- 12:46Speaker 1: such as BPC one fifty seven that's part of the
- 12:49Speaker 1: Wolverine Stack fabled wolverine stack KPV and TP five hundred
- 12:54Speaker 1: for bulk compounding. That gives compounding pharmacies here in the
- 12:58Speaker 1: US the ability to mix that into stuff that you
- 13:00Speaker 1: can then inject into yourself. A bit of controversy here
- 13:05Speaker 1: because the staff at the FDA recommended against this. They
- 13:09Speaker 1: cited lack of safety and efficacy data, which which we
- 13:11Speaker 1: of course highlighted in our prior episode. There's some interesting
- 13:14Speaker 1: rat data on some of these things, but in general,
- 13:17Speaker 1: we expect there to be human safety and efficacy data
- 13:20Speaker 1: before the FDA approves something. The panel that voted to
- 13:24Speaker 1: approve it had. It won't surprise you to hear been
- 13:27Speaker 1: recently reconstituted by RFK Junior. The new members include six
- 13:33Speaker 1: people who run businesses selling peptides, okay, which is like,
- 13:37Speaker 1: I don't know, it's okay. I understand that you want expertise,
- 13:42Speaker 1: and a lot of times experts do have relationships with industry,
- 13:45Speaker 1: and that's true, but you know, the people that run hhs,
- 13:49Speaker 1: including RFK, really criticize the FDA for having people with
- 13:53Speaker 1: industry ties on these panels. And now they have people
- 13:55Speaker 1: who run clinics in Florida that make money injecting overseas
- 13:58Speaker 1: peptides on these panels.
- 14:00Speaker 2: Okay, so to play to play Devil's advocate on this
- 14:03Speaker 2: question of like whether we should have proved these I
- 14:05Speaker 2: think they do. There is an argument which the panel made,
- 14:09Speaker 2: which is that people are already using these and they're
- 14:12Speaker 2: getting them from these unsafe overseas sources, and if we
- 14:16Speaker 2: provide them in the US, they will get them here
- 14:19Speaker 2: and that will be safer for me. That trades off
- 14:22Speaker 2: against the fact that if you provide them here in
- 14:24Speaker 2: the US, many more people will use them.
- 14:26Speaker 1: Yeah. And it's also it's like, that's like cool mom energy, right,
- 14:29Speaker 1: It's like, I know you guys are going to be drinking.
- 14:31Speaker 1: I'd rather you drank here, like and I got you
- 14:34Speaker 1: a bunch of vodka, Like I.
- 14:35Speaker 2: Just that's the at some White Claw and some Social
- 14:39Speaker 2: Tonics so you can try things out.
- 14:41Speaker 1: Yeah, the FDA is supposed to do.
- 14:43Speaker 2: It's not a regular mom, the FDA. It's cool, mom,
- 14:45Speaker 2: it's cool.
- 14:46Speaker 1: It's cool. FDA. Just like do safety and efficacy. That's
- 14:49Speaker 1: like your whole thing, Like prove that a drug works,
- 14:51Speaker 1: prove that it's safe. That's what we have to do.
- 14:53Speaker 1: And maybe these things do work, but you got to
- 14:56Speaker 1: run the trials. It feels like the bare minimum, and
- 14:58Speaker 1: like this is what they complain about with vaccines. They're like, ah,
- 15:01Speaker 1: they haven't gone through adequate trials, which again is untrue,
- 15:05Speaker 1: but in this case it is true. But all of
- 15:07Speaker 1: a sudden, it doesn't matter because we can make a
- 15:08Speaker 1: lot of money, like with these things that aren't going
- 15:11Speaker 1: to be covered by insurance being sold in wellness clinics
- 15:14Speaker 1: without any evidence except for social media clout.
- 15:17Speaker 2: All right, well, so before you buy a wolverine stack,
- 15:19Speaker 2: please listen to our last episode about the data. Thank you.
- 15:23Speaker 2: All right, that's it for the health news of the week,
- 15:25Speaker 2: and now let's dive into the sun, not literally, let's
- 15:30Speaker 2: dive into information about the sun.
- 15:33Speaker 1: Do you know what happened to the sun if you
- 15:36Speaker 1: were to put a human body into it?
- 15:39Speaker 2: I don't think you could get that close to the
- 15:41Speaker 2: sun with that magically, Like.
- 15:42Speaker 1: If you magically transported a human body into the sun,
- 15:44Speaker 1: you know what happened to the sun?
- 15:46Speaker 2: Nothing?
- 15:47Speaker 1: Nothing, nothing, nothing at all.
- 15:49Speaker 2: I think what happened you know what happened to the human?
- 15:51Speaker 2: Not anything good? Nothing good.
- 15:53Speaker 1: It's not good for the human, not.
- 15:55Speaker 2: Good for you. All right, So I think it's worth
- 15:59Speaker 2: asking the question, why are we talking about the sun?
- 16:02Speaker 2: What does it mean to ask what's the deal with
- 16:04Speaker 2: the sun? And obviously we should say the sun is
- 16:06Speaker 2: crucial for life on Earth, not controversial, that's not controversial.
- 16:11Speaker 2: But on Instagram there are some more controversy about the sun,
- 16:16Speaker 2: not about whether we should have it, but about your
- 16:19Speaker 2: relationship to exposure to it. And so in particular, I
- 16:22Speaker 2: read an increasing sense that maybe we should be more
- 16:26Speaker 2: exposed to the sun, right like we just like to
- 16:29Speaker 2: back up, I was born in the nineteen eighties, and
- 16:32Speaker 2: in the nineteen eighties we had a lot of sun exposure.
- 16:34Speaker 2: You know. One time I got a sunburned so bad
- 16:36Speaker 2: that my face blistered because we weren't just like wearing
- 16:39Speaker 2: that much sunscreen. And now it's like my kids are
- 16:43Speaker 2: in like a hat and full on sunscreen and like
- 16:45Speaker 2: a long sleeve bathing suit. There were no long sleeve
- 16:48Speaker 2: bathing suits when we were children. Now everyone's in like
- 16:51Speaker 2: a parka, like a beach parka. And so then the
- 16:55Speaker 2: Instagram has pushed back a little and be like, hey,
- 16:57Speaker 2: we're not you know, you're wearing too much sunscreen. Instead,
- 17:00Speaker 2: you should need a lot of watermelon, because that's just
- 17:03Speaker 2: as good as sunscreen.
- 17:04Speaker 3: Okay, here's an idea for you. Instead of lathering on
- 17:07Speaker 3: chemically filled, unnatural sunscreens, what if instead you drank some
- 17:11Speaker 3: watermelon juice. It's true, watermelon juice acts as a natural sunscreen.
- 17:16Speaker 3: Watermelon has something known as lycopine in it, which contains
- 17:19Speaker 3: antioxidant and anti inflammatory properties that help hydrate and nourish
- 17:24Speaker 3: the skin to protect it from the sun. It's well
- 17:26Speaker 3: known that hydrated and nourished skin is far less likely
- 17:30Speaker 3: to be damaged from the sun.
- 17:31Speaker 2: So I think that's what we're going to kind of
- 17:33Speaker 2: talk about here, like exposure to the sun, health, vitamin D, sunscreen,
- 17:37Speaker 2: mood disorders.
- 17:39Speaker 1: I love it.
- 17:39Speaker 2: What questions do you have about the sun?
- 17:41Speaker 1: It's the summer, so the sun is on my mind
- 17:44Speaker 1: and it's very hot. No, I think there's a lot
- 17:47Speaker 1: of good stuff to talk about here when you mentioned
- 17:49Speaker 1: sun when we were kids, totally, I once got a
- 17:52Speaker 1: sunburn on my forehead and like my skin was gonna
- 17:55Speaker 1: peel off but hadn't yet, so like there was a
- 17:57Speaker 1: layer of skin that was kind of loose, and I
- 17:59Speaker 1: was like eleven, and I remember looking in the mirror
- 18:01Speaker 1: and raising my eyebrows, and like all these wrinkles appeared
- 18:04Speaker 1: on my forehead and I thought, oh my gosh, I
- 18:07Speaker 1: have become old, Like the sun has given me wrinkles.
- 18:11Speaker 1: That's what everyone says the sun does. And then three
- 18:14Speaker 1: days are so passed, and that dead skin all kind
- 18:16Speaker 1: of fell off and I had a nice smooth forehead again.
- 18:18Speaker 1: But that image burned into my memory. And then about
- 18:21Speaker 1: ten years ago, I was looking in the mirror and
- 18:24Speaker 1: I raised my eyebrows and there they were again for
- 18:29Speaker 1: real time. And the prophecy has been fulfilled.
- 18:33Speaker 2: All right, So let's start, I think talking about sunscreen,
- 18:39Speaker 2: because sunscreen is weirdly controversial. Actually, yeah, I don't know
- 18:46Speaker 2: what happened there.
- 18:46Speaker 1: I mean, I think we can unpack why it's controversial. Well, okay, overall,
- 18:52Speaker 1: there's money to be made in controversy, right if you're
- 18:54Speaker 1: an influencer and you kind of are going to be
- 18:56Speaker 1: a contrarian and say, like, well, all the nerds the
- 19:00Speaker 1: Ivory Tower telling you to wear sunscreen, now I'm going
- 19:02Speaker 1: to tell you not to. And by the way, you know,
- 19:03Speaker 1: buy my product or whatever. Like there's there's always the grift,
- 19:07Speaker 1: and we should just say that but I think we
- 19:09Speaker 1: can find some other reasons that people are skeptical of sunscreen.
- 19:12Speaker 1: The reason we wear well, there's two reasons we wear
- 19:15Speaker 1: sunscreen really. One is to prevent skin cancer, and one
- 19:20Speaker 1: is to prevent the solar aging. The fact that it's true,
- 19:25Speaker 1: although it didn't happen to be when I was ten,
- 19:27Speaker 1: the sun does age your skin. And you know, I
- 19:31Speaker 1: think just i'll briefly touch on mechanism here. I think
- 19:35Speaker 1: the only thing that we need to take home is
- 19:37Speaker 1: that the sun. The bad stuff that comes from sunlight
- 19:40Speaker 1: not bad. The potentially damaging stuff are uv A and
- 19:44Speaker 1: uv B wavelengths of light. If you go all the
- 19:47Speaker 1: way back to our red light therapy episode, you'll remember
- 19:50Speaker 1: that the shorter wavelengths have more energy, they can kind
- 19:53Speaker 1: of do more damage, but they don't penetrate as deeply.
- 19:56Speaker 1: UVB has that shorter, high energy stuff that can damage DNA,
- 20:02Speaker 1: and that's one of the mechanisms by which this causes cancer,
- 20:05Speaker 1: whereas the UVA, which can get a little deeper, actually
- 20:08Speaker 1: might be more responsible for aging. You know, sunspots, wrinkling
- 20:13Speaker 1: and stuff like that, And of course sunscreen. We'll dig
- 20:18Speaker 1: into a little bit of how sunscreen works, but sunscreen,
- 20:21Speaker 1: if you're wearing a good one, will block both of
- 20:23Speaker 1: these things.
- 20:25Speaker 2: Both the sun and tanning beds provide the same thing.
- 20:28Speaker 2: So some nice people will talk about tanning beds being.
- 20:31Speaker 1: Worse or better.
- 20:32Speaker 2: I think that for the most part, what we are
- 20:35Speaker 2: going to say here applies to using a tanning bed
- 20:38Speaker 2: or being outside. Maybe there's some small differences here.
- 20:44Speaker 1: Yeah, I would just think of tanning beds as the
- 20:47Speaker 1: same as sun. There's a little weird stuff. There's an
- 20:51Speaker 1: interesting article in Science Advances in twenty twenty five about
- 20:54Speaker 1: this that showed that the melanocite mutation burden was high
- 21:00Speaker 1: and distributed more broadly, and people use tanning beds. People
- 21:04Speaker 1: use tanning beds are also more likely to get multiple
- 21:06Speaker 1: primary melanomas. So a primary cancer is like a cancer
- 21:11Speaker 1: in a spot, as opposed to metastatic, which has spread
- 21:13Speaker 1: from somewhere else, And so multiple primaries is like getting
- 21:16Speaker 1: cancer twice. But these are all really kind of marginal
- 21:19Speaker 1: on the edge stuff. I wouldn't like consider one being
- 21:22Speaker 1: safer than the other.
- 21:23Speaker 2: I will say I don't think people should use tanning. Like,
- 21:26Speaker 2: if you are looking to be tan there's a spray
- 21:29Speaker 2: for that. You know, like if your goal physical tanning experience,
- 21:33Speaker 2: like to look tan, you should just go spray tan yourself.
- 21:36Speaker 1: Hey, there's also a peptide for that.
- 21:38Speaker 2: There's also a peptide for that. Now you could probably
- 21:40Speaker 2: get it. And so I would like sort of put
- 21:43Speaker 2: that aside, because for many people the question is more,
- 21:46Speaker 2: you know, I'm going to be outside, and then therefore
- 21:50Speaker 2: you know should or should not? Should I not protect myself?
- 21:55Speaker 2: And I will say the debate on both sides is
- 21:59Speaker 2: basically about cancer. So the reason that people that we
- 22:03Speaker 2: think you should wear sunscreen is because of cancer, And
- 22:06Speaker 2: a lot of the reason people think you shouldn't wear
- 22:08Speaker 2: sunscreen is also about cancer. Maybe some about endocrine disruption,
- 22:12Speaker 2: but like, cancer comes up on both sides of this,
- 22:14Speaker 2: and sometimes the same kinds of cancers, and the conversation
- 22:19Speaker 2: is confused.
- 22:20Speaker 1: Yeah, let me play you a clip from a typical
- 22:25Speaker 1: influencer that people see online talking about the dangers of sunscreen.
- 22:31Speaker 4: I am the single biggest hater of sunscreen on the planet.
- 22:33Speaker 4: I stopped using sunscreen two years ago when I found
- 22:35Speaker 4: out all the problems with it, and I'm never going back.
- 22:37Speaker 4: For starters, the lie that we've heard is that sunscreen
- 22:39Speaker 4: helps protect you from melanova and skin cancer. Sunscreen wasn't
- 22:43Speaker 4: invented until the nineteen thirties, and I believe it wasn't
- 22:44Speaker 4: brought to the United States until the mid nineteen forties,
- 22:47Speaker 4: but it didn't get FDA approved until about nineteen eighty.
- 22:50Speaker 4: Since nineteen eighty, we've seen an increase of over seven
- 22:53Speaker 4: hundred percent of Melanova cases. Hmmm, but I thought it
- 22:56Speaker 4: was supposed to protect us from the sun. That's what
- 22:58Speaker 4: all the dermatologists say.
- 22:59Speaker 2: Who cares rated their education, right, This guy's confused.
- 23:04Speaker 1: This guy is shirtless too, Emily, is this do we
- 23:08Speaker 1: need to do this? Do we need to be recording
- 23:09Speaker 1: our podcast without our shirts on? Because apparently this is
- 23:12Speaker 1: how you get engagement nowadays.
- 23:13Speaker 2: Yeah, are you gonna? I think you should. We we'll
- 23:16Speaker 2: see how it goes, and then if we have to
- 23:18Speaker 2: ramp up to me, we'll try that anyway. Okay. So
- 23:22Speaker 2: the claim here is that sunscreen somehow causes skin cancer.
- 23:30Speaker 2: That's confused.
- 23:31Speaker 1: Yeah, I mean it's so this influencer is like, oh,
- 23:34Speaker 1: we started using sunscreen, you know, in the sixties, and
- 23:38Speaker 1: skin cancer rates have also gone up. A classic ecological
- 23:42Speaker 1: fallacy for the epidemiologists out there, but also a lot
- 23:47Speaker 1: of reverse causality, like sunning and getting tan was not
- 23:52Speaker 1: as much of a thing in the nineteen thirties and
- 23:55Speaker 1: forties that like was in fact, until people could travel
- 23:58Speaker 1: to exotic places and get tan and display that they
- 24:02Speaker 1: were wealthy by being tan. They used to display their wealth,
- 24:05Speaker 1: telegraph their wealth to others by being pale, to show
- 24:08Speaker 1: that they didn't have to like work in the fields
- 24:10Speaker 1: and stuff. And so it's sort of the ideal of
- 24:12Speaker 1: beauty to be very fair and pale and like, I've
- 24:14Speaker 1: never seen the sun. And then that started to change
- 24:17Speaker 1: as society changed and travel became easier. People wore more
- 24:20Speaker 1: sunscreen to avoid sunburns. People got more cancers because they
- 24:23Speaker 1: were in the sun more often. That's really all it is.
- 24:26Speaker 2: Yeah, I will also say detection rates for these things
- 24:29Speaker 2: have gone up over time, and so it is. You know,
- 24:32Speaker 2: in eighteen fifty, if you got a melanoma, you just died.
- 24:36Speaker 2: Nobody was like, hey, you know, let me screen you
- 24:39Speaker 2: every six months for a weird mole and take it
- 24:42Speaker 2: off and diagnose you. But then you're fine, you just died,
- 24:44Speaker 2: And so it's a bit weird. To say, you know,
- 24:47Speaker 2: and probably you died from something else first anyway.
- 24:49Speaker 1: So none of the chemicals in sunscreen have been associated
- 24:54Speaker 1: with cancer, None of them damaged DNA, none of them
- 24:56Speaker 1: have a mechanism by which they could cause cancer. If
- 24:59Speaker 1: I'm really like waving my hands and I want to
- 25:03Speaker 1: play Devil's advocate, I could say, well, maybe wearing sunscreen
- 25:07Speaker 1: gives you a false sense of security when you're out
- 25:10Speaker 1: in the sun, and so you sort of spend more
- 25:12Speaker 1: time in the sun and you don't reapply as often
- 25:15Speaker 1: as you should, and maybe that's a risk factor. But
- 25:17Speaker 1: you can't really blame the sunscreen for that, right, Like
- 25:20Speaker 1: it doesn't cause cancer.
- 25:22Speaker 2: And we have a fair amount of data that wearing
- 25:24Speaker 2: sunscreen reliably reduces cancer. So I think the best data
- 25:28Speaker 2: comes from Australia. So there's a trial published in the
- 25:32Speaker 2: late nineteen nineties sixteen hundred Australians. They were randomized to
- 25:36Speaker 2: either daily SBF fifteen or discretionary use, which just meant
- 25:40Speaker 2: use it whenever you want. Since people don't use do things,
- 25:43Speaker 2: they use less. Over a period about five years, there
- 25:47Speaker 2: was a thirty eight percent lower rate of I never
- 25:51Speaker 2: know how to scream.
- 25:52Speaker 1: Famous cell carcinoma.
- 25:54Speaker 2: Weamous cell carcinoma over eight years of follow up, and
- 25:58Speaker 2: there is a non significant but sizable reduction in the
- 26:04Speaker 2: number of invasive melanomas. Melanomas is fairly uncommon, so there
- 26:08Speaker 2: were only three invasive melanomas in the sunscreen group and
- 26:14Speaker 2: eleven in the other group. And so that's that's not
- 26:16Speaker 2: really enough to be statistically confident, but it is. It
- 26:19Speaker 2: is meaningful. I think that's our best. I think that's
- 26:22Speaker 2: our best randomized data.
- 26:23Speaker 1: It's a randomized trial. It wasn't even that much SPF.
- 26:26Speaker 1: I mean, fifteen is kind of on the low end
- 26:27Speaker 1: of what we would probably use today, and it's good.
- 26:31Speaker 1: The observational data, like influencers will pull out studies that
- 26:37Speaker 1: you can find studies that show people use sunscreen have
- 26:39Speaker 1: lower rates of cancer, Studies that show that people use
- 26:41Speaker 1: sunscreen have higher rates of cancer of skin cancers. So
- 26:46Speaker 1: much of this is what we call confounding by indication, right,
- 26:50Speaker 1: which is that people who are at higher risk use
- 26:53Speaker 1: more sunscreen.
- 26:54Speaker 2: Right.
- 26:54Speaker 1: Because it's not randomized, it's you see a similar thing.
- 26:58Speaker 1: I'm almost like has an to say it. People who
- 27:01Speaker 1: take statins have a higher risk of heart attack, overall
- 27:06Speaker 1: than the general population of people who don't take statins,
- 27:09Speaker 1: because people who take statins take them for a reason
- 27:12Speaker 1: because they're at higher risk of heart disease. They're older,
- 27:14Speaker 1: they have diabetes, they have high cholesterol, whereas an eighteen
- 27:16Speaker 1: year old who's perfectly healthy doesn't take a statin and
- 27:18Speaker 1: is unlikely to have a heart attack. So this is
- 27:20Speaker 1: all over the observational literature, which is why you need
- 27:23Speaker 1: randomized trials. We have one sunscreen reduces the risk of
- 27:26Speaker 1: skin cancer.
- 27:28Speaker 2: We call that reverse causality, not count but like in economics,
- 27:32Speaker 2: this thing, I mean, it is just like an interesting
- 27:34Speaker 2: like there's different words for this. We call it a
- 27:36Speaker 2: reverse causality, which I like better because I think it's
- 27:38Speaker 2: easier to say than confounding my indication, and it makes
- 27:42Speaker 2: more sense.
- 27:44Speaker 1: Well, cheerfully withdrawn, all right.
- 27:47Speaker 2: There are multiple kinds of sunscreen that one could use.
- 27:50Speaker 2: There is mineral sunscreen. This is the sunscreen that makes
- 27:53Speaker 2: your face white. It blocks with zinc or titanium dioxide,
- 28:00Speaker 2: and you two.
- 28:01Speaker 1: Can look like an eighteenth century consumptive.
- 28:05Speaker 2: Queen Elizabeth covered her face in lead, and you can
- 28:07Speaker 2: cover your face in zinc oxide and achieve the same
- 28:11Speaker 2: activity without the facial pitting.
- 28:13Speaker 1: Yeah, I was surprised actually to find I didn't actually
- 28:19Speaker 1: know this zinc oxide has broader spectrum coverage. So the
- 28:23Speaker 1: way these work, by the way, is just it's a
- 28:25Speaker 1: physical barrier, like the UV reflects off the tiny particles
- 28:29Speaker 1: of zinc or titanium and just reflects into a way
- 28:32Speaker 1: towards someone else. Zinc does that both for UVA and UVB,
- 28:37Speaker 1: whereas titanium is really UVB focused, and so some dermatologists
- 28:43Speaker 1: will recommend to make sure that if you're using titanium alone,
- 28:47Speaker 1: like you want to be using something else for UVA,
- 28:49Speaker 1: particularly because you don't want that skin aging effects For
- 28:52Speaker 1: those of you who don't want to look like eighteenth
- 28:53Speaker 1: century consumptives. These nanoparticle formulations that they have now are
- 28:58Speaker 1: a little less white. I don't know if you've tried them, Emily,
- 29:00Speaker 1: they look okay there and they seem to and medically speaking,
- 29:04Speaker 1: they're just as good as the other kinds.
- 29:07Speaker 2: They're also chemical sunscreens, and that is anything you're using
- 29:11Speaker 2: in a spray. There are other chemical sunscreens which are
- 29:14Speaker 2: using chemicals to block the UBA and UVB light. They
- 29:18Speaker 2: do not turn your face white. Some people are afraid
- 29:22Speaker 2: of these due to concerns about endocrine disruption from some
- 29:26Speaker 2: of the chemicals that are used in this. And we'll
- 29:29Speaker 2: say that if you feed a rat very very high
- 29:33Speaker 2: doses of some of the chemicals in these sunscreens over
- 29:36Speaker 2: their whole lifetime, it is not good for them and
- 29:39Speaker 2: their reproductive system. But the kinds of level of exposure
- 29:45Speaker 2: that you have as a person using the sunscreen is
- 29:48Speaker 2: very different than if you are a rat who's primarily
- 29:51Speaker 2: eating it. And in fact, people have looked carefully at
- 29:55Speaker 2: you know, how much would you have to use sunscreen,
- 29:57Speaker 2: like over your whole life cycle to get to this exposure,
- 29:59Speaker 2: and it's like not feasible. So I would say if
- 30:03Speaker 2: chemical sunscreen is the thing that is easier for you
- 30:07Speaker 2: or more acceptable, you should use that. And if you
- 30:10Speaker 2: like the white stuff, that's also great. And if you
- 30:12Speaker 2: want to just wear a lot of clothing instead that
- 30:15Speaker 2: is also okay, but less feasible for most people and
- 30:17Speaker 2: especially for kids.
- 30:20Speaker 1: Totally agree, whatever will make it easier for you to
- 30:22Speaker 1: use for the chemical sunscreen, So those chemicals also have
- 30:25Speaker 1: different levels of VA and UVB protection. The FDA has
- 30:28Speaker 1: an official labeling for stuff that covers both and it's
- 30:34Speaker 1: broad spectrum, so you do want a sunscreen that has
- 30:37Speaker 1: that broad spectrum coverage on it that's legally regulated.
- 30:42Speaker 2: Also, you don't need SPF three billion, so they will
- 30:47Speaker 2: sell very expensive spfs like SPF one hundred or is
- 30:50Speaker 2: it really make any sense given what I understand to
- 30:54Speaker 2: be what this means, But SBF thirty is the American
- 30:58Speaker 2: Dermatological Society says sp thirty or higher, So thirty to
- 31:02Speaker 2: fifty you do not have to have, you know, ninety nine,
- 31:05Speaker 2: which is expensive.
- 31:06Speaker 1: There is one part of sun hitting your skin that
- 31:10Speaker 1: I debated putting in this episode, Emily, but I think
- 31:15Speaker 1: we just have to talk about it, and that is
- 31:18Speaker 1: should we be sunning our perineums. Let me play you
- 31:25Speaker 1: a clip from Mister health Nut. Oh, this is a
- 31:29Speaker 1: good one.
- 31:30Speaker 5: Okay, here we are guys. You guys ask about the
- 31:33Speaker 5: butthole sunning all the time, and this is another one
- 31:36Speaker 5: of my practices. I don't always talk about it, but
- 31:39Speaker 5: it's well known that your fater or your butthole is
- 31:44Speaker 5: one of the most sensitive or thin mucous membranes in
- 31:48Speaker 5: the body. Thirty seconds of sun on the butthole is
- 31:52Speaker 5: like eight hours of sun outside with your clothes on,
- 31:55Speaker 5: and so let's basically, the sun is the source of
- 31:58Speaker 5: all energy, and so you're getting that sunlight up into
- 32:03Speaker 5: the channels of the body. You're giving yourself a nice
- 32:06Speaker 5: energetic electrical butt plug. For men, sun on your testicles
- 32:11Speaker 5: or naked sun is good for testosterone boostings. This is
- 32:15Speaker 5: just energy for the soul.
- 32:19Speaker 2: My favorite part of that Cliff Perry is when he
- 32:21Speaker 2: says he doesn't people don't talk about it all the time.
- 32:24Speaker 2: It's like, that's true, that's true. You talk about this
- 32:27Speaker 2: all that.
- 32:27Speaker 1: Can you describe what you're watching for people who are
- 32:29Speaker 1: listening to this in audio format.
- 32:31Speaker 2: There's a man. He's both shirtless and pantiless, although you
- 32:35Speaker 2: can't see too much, and his legs are over his head,
- 32:38Speaker 2: and it is obvious that he is exposing his butthole
- 32:43Speaker 2: to the sun while explaining the benefits of doing so.
- 32:48Speaker 1: This this is in the zeitgeist in no small part
- 32:52Speaker 1: because Tucker Carlson himself tried this. He had some documentary
- 32:58Speaker 1: on you know, being a man or manliness in America,
- 33:01Speaker 1: and some somehow this incredibly unmanly thing. Like I just
- 33:06Speaker 1: I look at this video and like this just does
- 33:08Speaker 1: not scream macho to me. Apparently boosts your testosterone or
- 33:13Speaker 1: something like that.
- 33:14Speaker 2: Yeah, I should say, your buttole and your paraneum are
- 33:16Speaker 2: actually not the same thing. So first of all, that's
- 33:20Speaker 2: not the scientific word for your anus. But there's the
- 33:24Speaker 2: paraneum is the area between your either vagina or your
- 33:29Speaker 2: scrotum and your and your butthole. So I guess all
- 33:32Speaker 2: of that area could be sunned, but don't do Yeah,
- 33:36Speaker 2: you get sunburned. That's the terrible way to get a terrible,
- 33:40Speaker 2: painful sunburn in a very uncomfortable area.
- 33:42Speaker 1: Absolutely, First of all, this doesn't work. There is some
- 33:46Speaker 1: data that human testosterone levels peak in late summer early autumn,
- 33:50Speaker 1: but that has nothing to do with your premium and
- 33:51Speaker 1: it probably doesn't even have anything to do with sun exposure.
- 33:54Speaker 1: There's multiple factors that change testosterone levels, so that's nothing.
- 33:59Speaker 1: And there's some risk here s digging in. So people
- 34:02Speaker 1: with psyriasis can get UV therapy, so ultraviolet lights to
- 34:08Speaker 1: treat the psoriasis. UV light is immunosuppressive to some extent.
- 34:12Speaker 1: That's one of the reasons that cancers can develop with
- 34:14Speaker 1: excessive UV exposure. But for psoriasis, you want to suppress
- 34:17Speaker 1: the immune system. And when they first started doing this,
- 34:21Speaker 1: they found that people getting UVA and B therapy for
- 34:24Speaker 1: psoriasis had a fourfold increase in genital tumors. And that
- 34:29Speaker 1: was because the skin around the genitals is very thin,
- 34:33Speaker 1: so that high energy uv B can penetrate to more
- 34:36Speaker 1: important stuff than it can in the other parts of
- 34:39Speaker 1: your body. And so now the guideline recommendations for people
- 34:42Speaker 1: getting that therapy even whole body u v A u
- 34:44Speaker 1: v B for psoriasis is to specifically cover the genital area,
- 34:49Speaker 1: the perineum. So don't do this, Okay, should take a break.
- 34:56Speaker 2: I feel like we're going to take a break. If
- 34:57Speaker 2: you need to go sun your buttthole, this is a
- 34:59Speaker 2: great time. And then come back and we'll talk about
- 35:03Speaker 2: vitamin D. Welcome back. We are going to turn to
- 35:12Speaker 2: vitamin D and whether the need for more vitamin D
- 35:17Speaker 2: is part of why you should be exposed to the sun.
- 35:21Speaker 2: Let me set the stage here by saying there are
- 35:24Speaker 2: many vitamins AC a bunch of different B vitamins. Most
- 35:30Speaker 2: of these you get through your food. Vitamin D is
- 35:35Speaker 2: one that you get some through your food but also
- 35:39Speaker 2: through exposure to the sun. Like other vitamins, if you
- 35:43Speaker 2: do not have enough of this, it's very bad. So
- 35:47Speaker 2: vitamins are in general substances that our body cannot produce
- 35:51Speaker 2: on its own, so we must be getting from some
- 35:53Speaker 2: outside source. Like extensive Vitamin D deficiency is associated with
- 36:00Speaker 2: with rickets in kids with kind of bone decay. You
- 36:05Speaker 2: need vitamin D to support to support your bone, but
- 36:08Speaker 2: you basically can't get enough of it through food, So
- 36:11Speaker 2: most foods don't have very much at all. Your milk
- 36:14Speaker 2: is fortified with that, but most people in the US
- 36:16Speaker 2: are not getting anything close to the appropriate amount of
- 36:19Speaker 2: vitamin D in food, and so they have to get
- 36:21Speaker 2: it through the sun. Okay, how does it happen, science Perry,
- 36:27Speaker 2: How do you get vitamin D through the sun. It
- 36:29Speaker 2: involves the kidney, So I'm going to give this to you.
- 36:31Speaker 1: Yeah, it does. So you have in your skin a
- 36:35Speaker 1: substance called seven D hydro cholesterol, which is a cholesterol derivative,
- 36:40Speaker 1: and UVB converts that to vitamin D three. So you've
- 36:46Speaker 1: probably seen D three supplements in the GENC or CBS
- 36:50Speaker 1: or whatever. That's what it is. Vitamin D three is
- 36:54Speaker 1: not active. It has no physiologic effects. But it is
- 36:58Speaker 1: a substrate that gets converted by the liver to twenty
- 37:00Speaker 1: five hydroxy vitamin D that is also not active. You
- 37:06Speaker 1: can get a prescription for that. This is called Ergo
- 37:09Speaker 1: calcifer All, but it's generally not sold in stores. That
- 37:13Speaker 1: twenty five vitamin D goes to the kidneys and becomes
- 37:16Speaker 1: one twenty five hydroxyl vitamin D, and that and only
- 37:21Speaker 1: that is the biologically active form of vitamin D. There's
- 37:25Speaker 1: a prescription form of that as well, called calci trial,
- 37:28Speaker 1: which is very expensive and has a lot of side effects.
- 37:31Speaker 1: But basically there's a lot of processes in your body
- 37:34Speaker 1: that are designed to get you to vitamin D and
- 37:36Speaker 1: it all starts with UVB exposure. But I think what
- 37:39Speaker 1: will surprise people is how much vitamin D you get
- 37:43Speaker 1: from a little bit of sunlight. So the recommended daily
- 37:50Speaker 1: intake for vitamin D is varies. Two hundred to four
- 37:53Speaker 1: hundred international units is sort of typical, and you'll see
- 37:56Speaker 1: supplements ranging from like one thousand to two thousand international
- 38:00Speaker 1: units per day vitamin D supplements. If you had UVB
- 38:05Speaker 1: exposure for twenty minutes to your whole body, so imagine
- 38:09Speaker 1: twenty minutes on the beach. If you're a light skinned individual,
- 38:12Speaker 1: and this is an important consideration, that produces approximately ten
- 38:17Speaker 1: thousand international units of D three, so about ten times
- 38:21Speaker 1: the dose you'd get from from taking a vitamin that's
- 38:24Speaker 1: twenty minutes.
- 38:26Speaker 2: It is also, I think important to say at this
- 38:29Speaker 2: point that you cannot overdose on vitamin D through the sun.
- 38:33Speaker 2: So you could if you were outside for a very
- 38:35Speaker 2: long time, like putting aside the sunburn risk, and you
- 38:38Speaker 2: say you were outside for five hours, and so it's
- 38:40Speaker 2: going to be you know, many bajillion units of vitamin
- 38:44Speaker 2: D that will just that does that does not cause
- 38:48Speaker 2: you to overdose, whereas taking that amount in a supplement
- 38:52Speaker 2: would actually be quite dangerous.
- 38:54Speaker 1: Thank you for saying that. Yes, the sun degrades vitamin
- 38:58Speaker 1: D three in the skin, so as it's making it,
- 39:02Speaker 1: if there's a ton there, it'll degrade and sort of
- 39:05Speaker 1: noth It puts the brakes on automatically, but it ingested.
- 39:08Speaker 1: Vitamin D three is its own thing. People can absolutely
- 39:11Speaker 1: overdose on this stuff. You can get something called milk
- 39:14Speaker 1: alkali syndrome fascinating. You can get very high calcium levels
- 39:19Speaker 1: which can cause a lot of things, kidney damage, coma arrhythmias,
- 39:25Speaker 1: bad stuff. I think though, the reason vitamin D comes
- 39:30Speaker 1: up a lot is that we have a slew of
- 39:33Speaker 1: studies linking low vitamin D level measured vitamin D. And
- 39:38Speaker 1: I'll just say, typically when people are measuring vitamin D
- 39:40Speaker 1: in the blood, they're often measuring twenty five vitamin D
- 39:44Speaker 1: that liver one before it gets the kidney. It's just
- 39:46Speaker 1: an easier test to run than the real vitamin D.
- 39:49Speaker 1: It's fine, but we have a slew of studies linking
- 39:52Speaker 1: low vitamin D levels to a variety of diseases. And
- 39:57Speaker 1: I listed a few. So vit D level increases the
- 40:01Speaker 1: risk of cancer. Well, vitamin D level increases the risk
- 40:03Speaker 1: of cardiovascular disease. Low vitamin D level increases the risk
- 40:07Speaker 1: of diabetes. Low vitamin D increases the risk of falls,
- 40:11Speaker 1: COVID all cause mortality. Like, looking at all that observational data,
- 40:15Speaker 1: you'd be like, oh my god, vitamin D is the
- 40:18Speaker 1: most important thing in the world. But Emily, we don't
- 40:23Speaker 1: like observational data. What are the randomized trials of vitamin
- 40:27Speaker 1: D supplementation show us?
- 40:29Speaker 2: The randomized trials of vitamin D supplementation show us that
- 40:33Speaker 2: there's nothing so they're actually a large number of randomized
- 40:36Speaker 2: trials on all of the outcomes that you have listed.
- 40:40Speaker 2: Some of it is the same trial looking at and
- 40:43Speaker 2: these trials are big, you know, twenty five twenty six
- 40:46Speaker 2: thousand people true placebo control trials, and they just don't
- 40:54Speaker 2: show anything. They just show no differences. When you supplement
- 40:57Speaker 2: people with vitamin D, it doesn't look any different. They don't.
- 41:00Speaker 2: Nothing different happens than if they weren't supplemented with vitamin D.
- 41:04Speaker 2: And this is because the observational data is driven by bias,
- 41:12Speaker 2: by the fact that the people who are taking the
- 41:13Speaker 2: vitamin D are different from the people who don't take
- 41:15Speaker 2: the vitamin D. And in fact, like before I get
- 41:19Speaker 2: off my high horse about this, we have for many
- 41:22Speaker 2: years been telling people to take vitamin D, like vitamin
- 41:26Speaker 2: D is good for you, take vitamin D to prevent cancer.
- 41:28Speaker 2: And so not only is there this baseline just like
- 41:31Speaker 2: people who take more vitamins tend to be positively selected
- 41:34Speaker 2: in various ways, but over time we've made that worse
- 41:38Speaker 2: with our advice. So we tell people take vitamin D,
- 41:40Speaker 2: and the people who take the vitamin D are also
- 41:42Speaker 2: the people who are doing all of the other things,
- 41:44Speaker 2: and so the problem has gotten like worse and worse
- 41:46Speaker 2: and worse over time. About a half of Americans take
- 41:49Speaker 2: a vitamin D supplement now, and if you look at
- 41:53Speaker 2: what half it is, it's also the half that's exercising
- 41:55Speaker 2: and eating vegetables and doing other the things that not smoking,
- 42:01Speaker 2: and so it just it's just a classic case where
- 42:04Speaker 2: like the observational data is super is super misleading.
- 42:08Speaker 1: Even people, even if you excludeople who are supplementing at all,
- 42:12Speaker 1: you do find observationally that lower level like blood level
- 42:15Speaker 1: of vitamin D associates with all these bad outcomes. But
- 42:18Speaker 1: the way I often describe it is that vitamin D,
- 42:20Speaker 1: your vitamin D level, if you're getting your vitamin D measured,
- 42:24Speaker 1: it's very much a lifestyle biomarker. Like if you are
- 42:28Speaker 1: the type of person who goes outside and gets sun
- 42:32Speaker 1: and exercises and touches grass, like you're going to have
- 42:36Speaker 1: and it's a very diet right with multiple sources of
- 42:38Speaker 1: vitamin D in it, you're going to have a higher
- 42:40Speaker 1: vitamin D level. Conversely, if you're a person who is
- 42:44Speaker 1: sick from other things, who is you know, has nutritional deficiencies,
- 42:49Speaker 1: who isn't getting outside and getting exercise, you're going to
- 42:51Speaker 1: have a low vitamin D level. It is a very
- 42:54Speaker 1: nice marker of kind of overall health, but that doesn't
- 42:58Speaker 1: necessarily mean that making the marker look better makes your
- 43:02Speaker 1: health look better. It's it's the canary in the coal mine,
- 43:05Speaker 1: and you know, bringing in a better canary or whatever
- 43:07Speaker 1: doesn't fix the coal mine. That's a bit of a
- 43:10Speaker 1: tortured analogy.
- 43:11Speaker 2: Sorry, can see I see where you were going with that. Yeah,
- 43:14Speaker 2: So from the perspective of the sun, I will say, like,
- 43:18Speaker 2: you know, you are probably getting enough vitamin D from
- 43:21Speaker 2: your exposure to the sun already, and you don't need
- 43:25Speaker 2: to either stand outside more in the sun for more
- 43:27Speaker 2: vitamin D, nor do you need to take a vitamin
- 43:30Speaker 2: D supplement.
- 43:32Speaker 1: Yeah, it is a bit harder of course in the
- 43:35Speaker 1: winter and in certain climates where the sun doesn't shine
- 43:37Speaker 1: as much, and it is certainly harder for darker skinned individuals.
- 43:41Speaker 1: That melanin that protects the DNA in your cells from
- 43:44Speaker 1: uv causing mutations also decreases the ability of UVB to
- 43:48Speaker 1: help synthesize vitamin D, and so if you are darker skinned,
- 43:53Speaker 1: there's more rationale for focusing on dietary intake of vitamin D.
- 43:59Speaker 1: I'm still not very pro supplement of vitamin D just
- 44:01Speaker 1: because even in the randomized trials, we don't see a
- 44:04Speaker 1: signal across any skin tone for benefit.
- 44:08Speaker 2: By and large, totally right, I'm a negative on vitamin
- 44:11Speaker 2: D supplements, even though my many people are always telling
- 44:16Speaker 2: me to take them, but I don't.
- 44:18Speaker 1: Nope, them don't do it.
- 44:21Speaker 2: All right, So the sun necessary for your vitamin D,
- 44:25Speaker 2: but you know, need more of it. Sunscreen very important.
- 44:29Speaker 2: There are other ways in which we have evolved to
- 44:32Speaker 2: like the sun in particular. It makes us happy. Yeah,
- 44:37Speaker 2: people like to go outside and be in the sun.
- 44:40Speaker 1: That's nice.
- 44:42Speaker 2: Yeah, I mean there, and we see this well, we
- 44:44Speaker 2: see it in observational data where you know, people spend
- 44:48Speaker 2: more time outside have a lower risk of depression. Is
- 44:52Speaker 2: that causal? I don't. I don't know, But we do
- 44:56Speaker 2: have evidence on seasonal effective disorder, which responds to light therapy,
- 45:00Speaker 2: So I think there's a sort of clear randomized trial
- 45:04Speaker 2: that supports a mechanism that light exposure makes us happier.
- 45:09Speaker 2: Seasonal effective disorder is actually a big problem in a
- 45:11Speaker 2: lot of these countries where it's really dark all the time.
- 45:15Speaker 1: Yeah, and it's interesting it does not appear to be
- 45:17Speaker 1: vitamin D mediated, so it's not that your vitamin D
- 45:21Speaker 1: gets low and that's what causes sadness, because vitamin D
- 45:24Speaker 1: supplementation does not improve seasonal effective disorder, but the blue
- 45:29Speaker 1: light therapy does. That's clear. As you say, from randomized trials.
- 45:32Speaker 1: A lot of the mechanism apparently is circadian sleep disruption,
- 45:37Speaker 1: and the blue light therapy is done early in the
- 45:39Speaker 1: morning to sort of reset your circadian clock. And if
- 45:43Speaker 1: there's any theme of the Wellness actually podcast, it is
- 45:45Speaker 1: that sleep is the most important thing and is tied
- 45:48Speaker 1: to everything else, and so I think this is yet
- 45:50Speaker 1: another example of that.
- 45:51Speaker 2: Yeah, sleep is very important.
- 45:53Speaker 1: Yes, I found a couple of other weird like sun
- 45:57Speaker 1: benefits that I'm curious what you think about out Emily.
- 46:01Speaker 1: One is some fairly consistent links between low childhood sun
- 46:08Speaker 1: exposure and subsequent multiple sclerosis. So multiple sclerosis is clearly
- 46:15Speaker 1: diagnosed more in the northern latitudes. And this is not
- 46:21Speaker 1: just a rich country, poor country thing, because even across
- 46:24Speaker 1: for example, the United States, like the further north you are,
- 46:27Speaker 1: the higher the risk of multiple sclerosis is. I don't
- 46:31Speaker 1: have a great mechanism for why this would be. But like,
- 46:34Speaker 1: it's not just one or two studies that have found
- 46:36Speaker 1: this link. And I don't know, what do you think?
- 46:41Speaker 1: Do you think that there's an MS sunlight?
- 46:42Speaker 2: Things a little hard to tell from studies that are
- 46:47Speaker 2: on this. Most of these are what's called the case
- 46:49Speaker 2: control study, and so they identify, you know, because multiple
- 46:55Speaker 2: sclerosis is not common. I mean, it's not vanishing were
- 47:00Speaker 2: but it's not like it's not a common thing, so
- 47:02Speaker 2: you don't see it that much in these large population studies.
- 47:05Speaker 2: The way these studies often work is they will take
- 47:07Speaker 2: a set of people who have the diagnosis and then
- 47:10Speaker 2: find some other people without the diagnosis, and you know,
- 47:13Speaker 2: compare them on feature like questions, they ask them survey questions,
- 47:17Speaker 2: other other characteristics. That kind of study has all of
- 47:22Speaker 2: the problems of basic observational data that you know, these
- 47:25Speaker 2: groups may differ for in many other ways. It also
- 47:28Speaker 2: has a problem that they differ in how you select them,
- 47:32Speaker 2: and you're asking about stuff often that happened in the past.
- 47:35Speaker 2: It's just it's not a it's not a very strong
- 47:38Speaker 2: empirical approach. It's sometimes the only approach that we have.
- 47:41Speaker 2: And so I don't want to like say, we should
- 47:43Speaker 2: never look at this, but it feels as an approach,
- 47:47Speaker 2: like something that would generate a hypothesis rather than prove one. Sure,
- 47:51Speaker 2: and so this sort of this feels like there's probably
- 47:54Speaker 2: something more clever someone could do to try to get
- 47:57Speaker 2: more of an answer here. We don't understand that much
- 47:59Speaker 2: about ms and what drives people. It seems clear that
- 48:03Speaker 2: there's genetic risks, but also the epigenetic issues and other
- 48:08Speaker 2: things that happen. So it's an interesting research area. My
- 48:12Speaker 2: guess is that sun exposure will not turn out to
- 48:14Speaker 2: be the most important feature here.
- 48:16Speaker 1: Fair enough, if it gives people motivation to get their
- 48:19Speaker 1: kids outside in the sun, hits you all for the good,
- 48:22Speaker 1: but make sure they're wearing their sunscreen.
- 48:24Speaker 2: There is actually some better evidence that outdoor time reduces myopia.
- 48:29Speaker 2: That's probably not just about the sun but about being outside.
- 48:32Speaker 2: Oh sure, and some of that is from randomized data.
- 48:34Speaker 1: Yeah, yeah, yeah, yeah. I guess it turns out that
- 48:39Speaker 1: I mean, I guess our moms were right, which is
- 48:41Speaker 1: like sitting too close to the TV is gonna ruin
- 48:43Speaker 1: your eyesight? Right, like you when you're outside, you're forced
- 48:46Speaker 1: to what is it accommodate your pupils to distance, which
- 48:52Speaker 1: flexes those muscles a little.
- 48:54Speaker 2: Bit, right, something like that. Yes, anyway, it's good to
- 48:57Speaker 2: go outside. Yeah, that's another theme of wellness. Go outside
- 49:01Speaker 2: and then also go to sleep, but not outside.
- 49:04Speaker 1: Right right, All right, Emily, I think it's time to
- 49:10Speaker 1: decide whether this sun thing is all it's cooked up
- 49:14Speaker 1: to be. Smash or pass the sun.
- 49:18Speaker 2: I'm a smash. I mean, you know, it has its limitations,
- 49:21Speaker 2: but I would say on the whole, I'm pleased that
- 49:23Speaker 2: we have the sun around, and I'm going to keep
- 49:27Speaker 2: I like to keep it.
- 49:28Speaker 1: I agree, smash the sun is one of my top
- 49:34Speaker 1: five stars.
- 49:36Speaker 2: What is your second favorite star? Is it Alpha cent Jerry?
- 49:40Speaker 1: Yeah, it's Rice actually, because that's where the pleasure planet
- 49:48Speaker 1: is in Star Trek. That's for tomorrow's husband.
- 49:51Speaker 2: I will say, I'm going to pass vitamin D supplements
- 49:55Speaker 2: because we also talked about that, and I'm going to
- 49:57Speaker 2: smash sunscreen. What about you?
- 50:01Speaker 1: I will pass on vitamin D supplementation and smash sunscreen.
- 50:06Speaker 2: Yes, amazing. All right, that's it for the sun your
- 50:10Speaker 2: mail back question of the week after the break. All right,
- 50:18Speaker 2: let's move to our question of the week, and if
- 50:20Speaker 2: you have a question, you can go to Wellness actually
- 50:22Speaker 2: dot FM and leave us a recording and we will
- 50:25Speaker 2: try to answer it all Right this week, here's a
- 50:29Speaker 2: question Hi, Emily and Harry set between my husband and me.
- 50:34Speaker 1: Which organs can you?
- 50:36Speaker 2: No?
- 50:36Speaker 1: Thanks, this is such a fun question.
- 50:39Speaker 2: It's the kidney, right, you only need one of those.
- 50:42Speaker 2: I know they're your favorite, but it's not important.
- 50:44Speaker 1: Oh well, if we're saying we can only take out one,
- 50:47Speaker 1: then you can definitely take out one. Long that's fine.
- 50:50Speaker 1: You can take me half a liver basically. Oh sure, yeah, yeah, yeah.
- 50:53Speaker 2: Okay, so I could take I only knew one of
- 50:56Speaker 2: my lungs.
- 50:56Speaker 1: Come on, I was yeah. I mean, I'm not saying
- 50:59Speaker 1: it's going to be great, but you're you're you're fine.
- 51:03Speaker 1: You can take out people's hole lung all the time
- 51:05Speaker 1: for cancer and stuff like that. I thought this question
- 51:07Speaker 1: was the whole organ system, in which case I was
- 51:10Speaker 1: going to say kidney because of dialysis, because we don't
- 51:15Speaker 1: really have a die out, so kidneys clean the blood
- 51:18Speaker 1: and dialysis can kind of take over that for people
- 51:21Speaker 1: who have end stage kidney disease, which you would have
- 51:24Speaker 1: if both your kidneys were removed. It's it's not the
- 51:29Speaker 1: greatest thing in the world. You're getting four hours of
- 51:32Speaker 1: dialysis three times a week, but you you'd stay alive.
- 51:34Speaker 1: And we don't really have that. I'm trying to think,
- 51:36Speaker 1: we don't really have that for anything else.
- 51:37Speaker 2: I mean, what about your reproductive organs. We could take
- 51:40Speaker 2: out your your scuteris, your ovaries? Yeah, who needs no
- 51:46Speaker 2: problem not not using them all the time?
- 51:50Speaker 1: Yeap our producer to Mars's gallbladder. Sure you can remove that.
- 51:53Speaker 1: Is that an organ?
- 51:55Speaker 2: Is that an organ?
- 51:55Speaker 5: Yeah?
- 51:56Speaker 1: I don't think like a organ. Let's see brain you
- 52:01Speaker 1: probably need you know.
- 52:06Speaker 2: You remove your whole colon.
- 52:07Speaker 1: Yeah, we can get you can take out your whole colon.
- 52:09Speaker 1: That's that's done. M hm, spleen. Absolutely, you can do
- 52:16Speaker 1: without a spleen. Wow, we can remove a lot.
- 52:23Speaker 2: Let me ask you, Ferry, why did you choose to
- 52:25Speaker 2: be a doctor specializing in one of the organs we
- 52:27Speaker 2: don't need. Why didn't you pick an organ that is necessary?
- 52:31Speaker 1: Oh? That that does hurt a little bit, but it's
- 52:34Speaker 1: it's it's it's a good point. Do you know why.
- 52:36Speaker 1: It's because the kidneys are one of the few organs
- 52:40Speaker 1: where you can very easily measure the input which is blood,
- 52:43Speaker 1: the output which is urine, and infer the miracle that
- 52:48Speaker 1: is going on inside. Try that with anything any other organs.
- 52:52Speaker 2: Very difficult, spoken like a true lover of kidneys. Uh
- 52:58Speaker 2: in the human all right, so it turns out we
- 53:01Speaker 2: don't need many of our organs, but yet somehow, let's
- 53:05Speaker 2: just say there aren't. There's very few organs other than
- 53:09Speaker 2: maybe your reproductive organs where removing them even then probably
- 53:13Speaker 2: this we're removing them like would not result in some
- 53:16Speaker 2: change to how you would have to behave.
- 53:19Speaker 1: Yeah, yeah, yeah, they're there for a reason.
- 53:21Speaker 2: They're there for a reason evolution didn't. Except for the appendix,
- 53:24Speaker 2: which is a waste of time, most of our stuff
- 53:27Speaker 2: is useful. Okay, that's it. Join us next week when
- 53:33Speaker 2: we will ask what's the deal with gluten wellness? Actually
- 53:38Speaker 2: is produced in association with iHeartMedia. Our senior producer is
- 53:42Speaker 2: Tamar Avishai. Our executive producer at iHeart is Jennifer Bassett.
- 53:47Speaker 2: Our theme music is by Eric Deutsch, and our content
- 53:50Speaker 2: is for educational purposes only.
- 53:52Speaker 1: If you like the show, help other people find us,
- 53:54Speaker 1: leave a rating and review on Apple Podcasts, or your
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- 54:00Speaker 1: the show. You can follow us on Instagram at Wellness
- 54:03Speaker 1: Actually pod and don't forget we want to hear from you.
- 54:07Speaker 1: Head over to Wellness Actually dot fm and leave us
- 54:09Speaker 1: a question for our mailbag or suggest a topic for
- 54:12Speaker 1: a future show.
- 54:13Speaker 2: We'll let the influencers have the last word. The Sun
- 54:16Speaker 2: is a mass of incandescent gass, a gigantic nuclear furnace
- 54:20Speaker 2: where hydrogen is used into heale at temperatures of millions
- 54:23Speaker 2: of degrees.
- 55:11Speaker 1: Right, Oh, let's do the whole thing, because it's not rigel,
- 55:19Speaker 1: it's risa. They're gonna get me on that, all right,
- 55:29Speaker 1: except they said the wrong planet, all right, Emily, with
- 55:40Speaker 1: that the tough question, the Sun? Is it all? It's
- 55:45Speaker 1: cracked up to be? Smasher? Pass the Sun? H uh?
- 56:08Speaker 1: For the Sun? I will. I will smash the Sun.
- 56:11Speaker 1: It is one of my five favorite stars in the galaxy.
- 56:16Speaker 1: And I will pass on vitamin D supplementation and smash sunscreen.
- 56:22Speaker 2: Yes.
- 56:29Speaker 4: Hm,