Midnight Collapse: How Simufilam's Science Vanished and Patients Waited

Healthcare Scandal Investigations · Jul 22, 2026 · 19m

Midnight Collapse: How Simufilam's Science Vanished and Patients Waited

There is a slow-motion intellectual horror in this story: a drug tested by hundreds of Alzheimer's patients rested almost entirely on data from one lab, and by November 25, 2024 the Phase III trials had failed and simufilam was declared dead - but the original data was never produced. How did a molecule called simufilam and a protein called filamin A come to carry sixteen million dollars of public research investment, only to evaporate alongside a criminal case dropped at midnight?

In this episode, we trace the arc from…