Samuel Little: The Most Prolific Serial Killer in U.S. History and the 68 Women Still Nameless

When Killers Get Caught with Brittany Ransom · Mar 12, 2026 · 30m · transcript

Samuel Little is believed to be the most prolific serial killer in United States history, confessing to 93 murders across multiple states between the 1970s and early 2000s. For decades, many of his victims remained unidentified, their disappearances overlooked as Little traveled from city to city targeting vulnerable women.

In this episode, we examine the disturbing case of Samuel Little and the women whose lives were taken during his forty-year killing spree. After his arrest in 2012, investigators uncovered shocking confessions from Little that revealed a pattern of violence stretching…