Latest / Pediatrics Now: Cases Updates and Discussions for the Busy Pediatric Practitioner / Measles Outbreak Update: “It’s Heartbreaking”
Transcript
- 0:01I'm Holly Wehment, and this is Pediatrics Now, cases, updates,
- 0:05and discussions for the busy pediatric practitioner.
- 0:08Click on the link in this podcast for free credit that may include CME,
- 0:12MOC, or ethics credit, depending on our topic or podcast.
- 0:17Today, we're talking about something that is on a lot of pediatricians' minds, measles.
- 0:24Joining me here today, it's such an honor, Dr.
- 0:27Jason Bolling, Professor and Interim Chief, Division of Infectious Diseases,
- 0:32UT Health San Antonio and University Hospital.
- 0:35And he's also the Director of Hospital Epidemiology at University Health.
- 0:40Dr. Bolling, thank you so much for being here today on Pediatrics Now. Thank you for having me.
- 0:46What is the state? The big question, if we look at our community and in Texas,
- 0:51What's the state of measles right now?
- 0:54We are still experiencing the largest outbreak in the United States,
- 0:57in Texas, up in the panhandle region of Texas, with Gaines County being the
- 1:03epicenter of that, just south of Lubbock.
- 1:05The most recent numbers for that area are up to 717 confirmed cases,
- 1:11which, for context, there were 285 cases in the entire United States for all of 2024.
- 1:17So a large number of measles cases in Texas, that's our current state.
- 1:23And two children, as we know, have passed away from complications due to measles. That's right.
- 1:30Tragic deaths of two children, unfortunately, related to this outbreak,
- 1:33which again, largely centered up there.
- 1:35There have been other cases in Texas imported from travel to other areas,
- 1:38which also shows kind of this dynamic state of measles in Texas,
- 1:43but also globally, because these other people have traveled internationally
- 1:46and brought back cases that just haven't led to the large outbreak that we're
- 1:49seeing right now in the Gaines County area.
- 1:52In Bexar County, here in the San Antonio area, there have not been any reported cases as of yet?
- 2:00That's correct. Fortunately, we have not yet to date seen any confirmed cases
- 2:05in the Bexar County area.
- 2:06We're obviously keeping close track of that. Early on with the outbreak,
- 2:09there was somebody that was within their transmissible infectious window that
- 2:14traveled through the Bexar County region.
- 2:16And so there were some potential exposures. But fortunately,
- 2:19we didn't see any conversions, no confirmed cases. The closest county with a
- 2:23confirmed case to us is one in Atascosa County, which is a neighboring county to the south of us.
- 2:28But that is not related to the outbreak. It is thought to be related to travel.
- 2:33So that was one of the questions we had when we saw that case pop up.
- 2:37And we'll talk about the United States and the world where we have listeners
- 2:41around the world and throughout the United States.
- 2:43But here in Bexar County, the vaccination rate, it's my understanding,
- 2:48it's still high enough to have that firewall. Or is that what it's called to
- 2:52protect against an outbreak?
- 2:55Yes, we often call it the firewall. It's really the amount of people that you
- 2:59need in a community to have herd immunity, right?
- 3:01So there are definitely a few people in the community that can't receive the
- 3:09vaccine because of health conditions or wouldn't be expected to respond to the vaccine.
- 3:13Their immune system is suppressed. You can't give the vaccine to people that
- 3:17are on high-dose immunosuppressants.
- 3:20And so what you need is enough people in the community that have protection
- 3:24with antibodies so that if the disease is introduced, it doesn't spread from person to person.
- 3:28The ideal number for measles is really 95% or higher.
- 3:32So we are just under that, but we're above the national average,
- 3:36which is around 92.7%. And that's drifted down over the last few years,
- 3:40which is one of the reasons why we're seeing more measles cases today.
- 3:45Well, as we know, pediatricians, they often see 40 patients a day.
- 3:50And as we all know, kids get a lot of rashes for various reasons.
- 3:55Any insight you want to give regarding the measles, rash, measles symptoms?
- 4:00Yes. So rashes and fever can go together, particularly in the pediatric population.
- 4:05And so it can be tricky because there are other viral illnesses in particular that commonly cause it.
- 4:10So roseola is a really common one that could cause fever and a rash in very small children.
- 4:16That's caused by human herpes virus 6.
- 4:18You could see a rash with erythema, infectiousism, parovirus B19.
- 4:22And those can be more commonly seen.
- 4:25We have not seen a lot of measles since it's been declared eliminated in 2000,
- 4:30but obviously with this increased number of cases this year,
- 4:34people are understandably and appropriately on alert to look for measles. And so part of.
- 4:40Way to ferret that out or to tease that out when you're talking with a patient
- 4:44and the parents is to really ask them about recent travel, if they've been around,
- 4:48and particularly currently, if they've been in that outbreak area,
- 4:51that would be good to ask about from travel.
- 4:54And right now, saying here, Bexar County, it's my understanding the Department
- 4:58of Health is the place to send a patient to get tested, but it can be tough
- 5:02because they can only accept, there has to be a certain criteria in order to
- 5:07be tested. Is that correct?
- 5:09So generally, the tests that we send are a throat swab or an asopharyngeal swab,
- 5:14and then that is held. You also send blood tests for antibodies.
- 5:18If the antibodies are positive, then that swab gets sent through the health
- 5:23department to the state, and they send that for PCR to confirm that it's a true case of measles.
- 5:28So the blood tests generally get run with our labs here, and the health department
- 5:33requires that those be run and that they have a positive before they send the swab for the PCR test.
- 5:40So here locally, but is it still for that initial blood test?
- 5:45Is that done in the pediatrician's office and then sent to you at University Hospital?
- 5:50Or what's the process just to make sure?
- 5:52So it depends on the clinic. I think many clinics will send those tests out.
- 5:58The measles test gets sent out. And University Health is able to do an IgG test,
- 6:03but you send both an IgM and IgG antibody test.
- 6:07So at least one of those is a send out. And depending on your clinic setting,
- 6:10both of those may be sent out. And so there's a few days of waiting to see those results.
- 6:15And then that would trigger sending the swab for the PCR through the health
- 6:20department to the state lab.
- 6:22And so do the test in the clinic and then send it to University Hospital?
- 6:28Is that right? I, I, I, it will depend on the lab setup for,
- 6:33for the clinic that you're using.
- 6:36I'm so I, I guess I would, this is definitely something to look at now.
- 6:41It's unfortunately somewhat of a hassle that it's not something that we have,
- 6:44you know, available where you can get quick turnaround time.
- 6:46Cause every, obviously everybody would want to know the answer right away.
- 6:49I think there's some research ahead about where you would send serology testing
- 6:53and the swab would be held, would be good to check with your clinics that you
- 6:57would know in advance if you don't know already.
- 7:00Okay. And for the doctor listeners for clinics...
- 7:05They probably have a process in place, but if there's any specifics for here
- 7:08in Bexar County, you want to send me, you know, how to get, what's the best way to get a test?
- 7:14Or if there's anything you want to say here, let me know about that.
- 7:18Yeah, so I guess, yeah, I guess each clinic is a little bit different what labs
- 7:23they use. A lot of them you send out labs.
- 7:24So I don't know, like university health clinics would use the university health lab.
- 7:28And so they have a process, but other clinics are going to have different processes.
- 7:32It's kind of a hassle too, because it's two different tests,
- 7:34right? It's the blood test for the two different antibodies in the swab.
- 7:38But if people had questions, they could always call the MetroHealth to ask.
- 7:43Okay. So call, yeah, call MetroHealth.
- 7:47Anything else you want to say about, so is something that for you,
- 7:53you know, with your 15 years of experience in infectious disease,
- 7:57that you would really raise a red flag about, well, this really could be measles.
- 8:02Or could it look like something else until you get that test result?
- 8:08Yeah, and did you want to talk about complications from measles or why do we
- 8:13worry about measles or the numbers nationally?
- 8:17Yes, I would love to talk about that. I was just wondering for the pediatric
- 8:21practitioner, is there anything else you want to say about identifying measles?
- 8:25They don't want to have the family go through the alarm or having to go through
- 8:30the testing unnecessarily. necessarily.
- 8:32And then, of course, at the same time, of course, you don't want to miss it.
- 8:35You know, so is there anything else you want to say there regarding identifying who needs to be tested?
- 8:40Or is your advice like, better to be safe and sorry, go ahead and test if you suspect it?
- 8:46Yeah, sure. So I think it's important to kind of review the clinical course
- 8:51of measles because, again, it's not something that we've seen a lot of cases
- 8:55of until this big outbreak.
- 8:57Since it was declared eliminated in 2000, we've been fortunate to not have to
- 9:01worry a lot about what the clinical course looks like.
- 9:03And it's important because it can help to distinguish measles from other viral
- 9:08rash syndromes. Most people tend to have their symptoms initially start about
- 9:1410 to 12 days after their exposure.
- 9:17So really within the one to two weeks after their exposure can be as far out
- 9:20as three weeks from exposure.
- 9:21But the point is there's a delay from the potential exposure to when someone
- 9:25will start to first have symptoms.
- 9:27And the first symptoms are really nonspecific, which can make it really challenging.
- 9:31People start off with a fever, a cough, runny nose, and then itchy, watery eyes.
- 9:36And just that description alone is really nonspecific, right?
- 9:39That's what we see with a lot of people with viral upper respiratory infections,
- 9:42which are still circulating, right? We're moving out of respiratory virus season.
- 9:45You don't see the rash, the characteristic rash, develop until about three to
- 9:49four days after those nonspecific symptoms.
- 9:52And that is a little bit tricky. The rash is pretty characteristic.
- 9:56It usually starts with the face near the hairline as these flat brown or red spots.
- 10:02It then kind of moves down the face to the trunk of the arms and legs.
- 10:06So it moves from top to bottom.
- 10:08And then that characteristic rash can make it a little bit easier to identify
- 10:12that someone has measles.
- 10:14And that rash lasts for about a week before it goes. And it's usually accompanied with very high fever.
- 10:19And usually with our upper respiratory illnesses, we may see some fever.
- 10:21But fever with measles can be as high as 104 degrees.
- 10:24So it can be pretty high. People are considered infectious from four days before
- 10:28the rash, which is tricky, right?
- 10:31Because that's when they're having those nonspecific symptoms to four days after the rash.
- 10:35So if someone develops that rash, if one of your patients develops that rash,
- 10:39you'd want them to be seen, but you'd want them to contact the clinic first if possible.
- 10:43So you can make arrangements to move them into a private room,
- 10:46put a mask on them, and then make sure whichever people on the health care team
- 10:50are seeing this patient, even if they're fully immunized, should still wear
- 10:54a respirator, an N95 respirator, to make sure that they're protected.
- 10:58Because could they be contagious with the virus if they're vaccinated, kind of like with COVID?
- 11:04The patient or the healthcare provider? The patient who's vaccinated against,
- 11:09or were you saying even if the healthcare provider is vaccinated,
- 11:12he or she should wear a mask?
- 11:15Correct. So if the healthcare provider, even if the healthcare provider is fully
- 11:19immunized, and most healthcare providers are fully immunized,
- 11:22which is great, it's still recommended to wear an N95 respirator,
- 11:25even though the measles vaccine is very, very protective,
- 11:2897% protective if you've had two doses.
- 11:31There's obviously a 3% chance, right? And so you don't want to take any risks.
- 11:34And so wearing an N95 respirator for the healthcare provider,
- 11:37in addition to being vaccinated, is the way to protect yourself while you're
- 11:41examining the patient, testing the patient, interacting with the patient, the family members.
- 11:46And as we know, the measles, it can float in the air for some time, right?
- 11:51That's absolutely right. So one of the challenges with measles,
- 11:53it's one of the most transmissible pathogens we know.
- 11:56It's one we use as an example when we're looking at outbreak models.
- 12:01Up to 90% of people that are susceptible to measles, meaning they haven't been
- 12:05immunized or had measles, if they're exposed, will develop disease.
- 12:08That's a really high infection rate.
- 12:11And it lingers in the air in these tiny little droplets.
- 12:14And they can linger in the air up to two hours, as you mentioned.
- 12:16It's been tested up to two hours after someone that's infected with measles leaves a room.
- 12:21They leave this plume of infectious particles that sits there for up to two hours.
- 12:25And the other challenging part is, again, you're considered infectious for up
- 12:29to four days before that rash starts, where you're having those nonspecific
- 12:33symptoms that sound a lot like an upper respiratory infection.
- 12:35So it has some elements to it that make it very easy to transmit to others,
- 12:41transmitting before you would suspect that it's measles. And then it has this
- 12:44really high attack rate.
- 12:46It just sounds scary. It's a very, very concerning disease, which is why it's
- 12:52so heartbreaking to see us lose some of the ground that we've made from being
- 12:57declared eliminated to 2000 to where we're sitting at here in 2025.
- 13:01That's a great way to put it, Jason. Would you recommend, so say if there was
- 13:07a patient, you don't know yet if he or she actually has the measles.
- 13:11Whoever's been helping that patient in the exam room has an N95 on.
- 13:15After that, not have anyone in that room for the rest of the day?
- 13:19Or what would you recommend there in the pediatric practitioner setting where
- 13:23they're seeing a high volume of patients?
- 13:26Sure. Yeah, that's a tricky issue, right?
- 13:29Because you don't want to mess with the workflow too much. You don't want to
- 13:31expose patients either.
- 13:32Uh, so they need to be, that room needs to be left empty for at least two hours
- 13:36after this suspected measles patients with suspected measles has left the room.
- 13:42So there's enough time for ventilation to change that out.
- 13:45Some people will let it sit for a bit longer and be conservative.
- 13:49And can it go through the vents to other rooms? Well, in a hospital setting, so the answer is yes.
- 13:57So ideally, in the hospital setting, we have prolonged stays of these patients.
- 14:02We place them in an airborne infection isolation room, and that has dedicated
- 14:06exhaust that goes directly outside.
- 14:08It doesn't connect to the air conditioning for all of the other vents.
- 14:11In the outpatient setting, most outpatient settings don't have that type of
- 14:15room, but they're also not seeing the patient for such a prolonged time period.
- 14:19And so really the recommendation in the outpatient setting or where you don't
- 14:22have an airborne infection isolation room is to put them in a private room and
- 14:26then again let that room air out, as we talked about, ventilate after that patient has left the room.
- 14:31There's less risk for transmission through the ventilation system if they're
- 14:36there for a shorter period of time.
- 14:37In the inpatient setting where they're sitting for days potentially, you have a higher risk.
- 14:42Like we saw with COVID, a lot of clinics were testing patients outside.
- 14:47I mean, it's really hot right now in San Antonio, but is that something,
- 14:52if a clinic is set up to do that, is that something that you would recommend?
- 14:58If we started seeing confirmed cases, we may have to start looking at something
- 15:03similar, yes, to try and help reduce the risk of other patients in the clinic being exposed.
- 15:08If we were to start to see an outbreak here, we would need to look at what would
- 15:12be the most effective way to do screening and testing of people that we're presenting with symptoms.
- 15:17And this is even more infectious than COVID, right?
- 15:22Yes, much more infectious than COVID. So we talked about that 90% infection rate.
- 15:27So 9 out of 10 people that are susceptible that are exposed will get infected.
- 15:32With COVID, that number is much lower. It kind of depends depending on immune
- 15:37status. If you've been vaccinated or had COVID, which most people at this point
- 15:40have, most people are protected. But the attack rate for COVID is closer to
- 15:45like 40% to 60%. So much, much lower than measles.
- 15:48How worried are you about the current state of things?
- 15:53I'm very concerned that we could potentially move to where we have to worry
- 15:57about measles on a regular basis.
- 15:59Part of that is because of this large outbreak, but more concerned by the fact
- 16:03that we have now 31 jurisdictions in the United States.
- 16:06So that's 30 states, and then New York City is listed as its own jurisdiction
- 16:10that have reported cases.
- 16:11And so it's over half of the states in the U.S. now have confirmed cases.
- 16:16And most of those started off with an imported case because globally,
- 16:20measles is really high right now.
- 16:22We have had some decrease in our firewalls we talked about before,
- 16:26the number of people that are fully immunized.
- 16:29We were about 95% in 2019, so right before the pandemic.
- 16:33But we have drifted down to the national average being around 93%.
- 16:38So that decrease is worrisome because that increases the chances that one of
- 16:43these imported cases could lead to another outbreak.
- 16:46And if you look at the map, the CDC has a nice map where they show percentage
- 16:50vaccine rate in different states.
- 16:53There are some states like Idaho, which is all the way down at 79%.
- 16:57And so they're at much higher risk for an outbreak occurring there if they get an imported case.
- 17:01So those things are what concern me that we're going to see ongoing activity
- 17:05for a while, not just this huge outbreak, obviously, that's worrisome in the
- 17:09Panhandle region, but the number of cases throughout the U.S. right now.
- 17:13For our listeners in Idaho and in the Texas Panhandle, those are the two real
- 17:18hotspots right now, it sounds like.
- 17:20They don't have any ongoing cases in Idaho, but just looking at areas of vulnerability
- 17:25based on where that vaccine uptake rate is.
- 17:28And they basically use the data from kids that are entering kindergarten,
- 17:32school-age children, and they have a lower percentage uptake compared to some of the other states.
- 17:38It almost sounds like it's like the tsunami or hurricane warning.
- 17:43That's right. There are different risks depending on where you're at and then,
- 17:46you know, how much influx of travelers you have and where your vaccine firewall
- 17:50immunization rate is at.
- 17:53Is there one thing with, you know, pediatric practitioners are so busy as are
- 17:59family practitioners and seeing 40 patients a day.
- 18:02Given the state of things, is there one line you would hope that could be said in between,
- 18:09I mean, asking are you vaccinated or any thoughts there if we could have a crystal
- 18:16ball and everybody say something to help the situation?
- 18:19I know a lot of doctors feel pretty helpless right now regarding this.
- 18:24Sure. Yeah, I understand that too.
- 18:27It's discouraging. There is an overall increase in some vaccine hesitancy.
- 18:34But what I would say I look at, it's optimistic,
- 18:38and it is the silver lining, is that when patients are polled and surveyed,
- 18:43they do look to their pediatrician as a source of truth, a credible source of information.
- 18:49And so I think starting that conversation about vaccines is really important.
- 18:55Understandable that people might
- 18:56have questions. But I think starting a conversation is the best thing.
- 18:59And pediatricians are great about this, about talking with families.
- 19:03I would encourage everyone to continue having those conversations with their
- 19:07patients and families so that they can get those questions answered because they do listen.
- 19:12Even if it doesn't seem like they may be listening, they do listen.
- 19:16There's good published data showing that doctors are still considered an excellent,
- 19:21consistent source of truth.
- 19:23That's great reassurance, Jason. And we do have in this Pediatrics Now newsfeed
- 19:28our previous, two previous episodes on motivational interviewing.
- 19:32And our expert in the Department of Psychiatry addresses specifically how to
- 19:38utilize motivational interviewing to talk about vaccines.
- 19:42So hopefully that's helpful. And is your hope for it to be mentioned in each
- 19:48visit if you haven't seen a patient in a couple of months or anything you want to say there?
- 19:52Yeah, I think motivational interviewing and finding out ways,
- 19:56some scripting that you can use when you're busy to engage in these conversations
- 20:00is really helpful, and it's good to know that there's resources for that available.
- 20:06It is something that needs to be talked about. There's strategies such as when
- 20:09a patient is there saying,
- 20:10well, today we have your vaccine scheduled, as opposed to asking if you want
- 20:14a vaccine, because that kind of highlights that you're endorsing it as an important
- 20:19part of their care, and they can, of course, decline it if they don't want it,
- 20:22but knowing that you're recommending it, I think is also something that helps.
- 20:26It's a positive nudge towards what we would want them to do,
- 20:29which is take the vaccine.
- 20:31Jason, do you have anything you want to say to our pediatric practitioner listeners
- 20:37worldwide? We have listeners in Ukraine.
- 20:40We have listeners in Israel, in Africa. Anything you want to say there?
- 20:45I would encourage everybody to keep up the good work.
- 20:50It's really important for people to continue the physician-patient relationship and dialogue.
- 20:55Everybody is really busy, but it's really important that we continue this conversation
- 21:01and endorsement of vaccines.
- 21:03They're the most effective public health strategy we have for reducing infections.
- 21:08So we deal with infections when they come up, but the more that we can prevent,
- 21:12the better off that we are and we can avoid unnecessary morbidity and try to
- 21:18take deaths from vaccine-preventable illness.
- 21:20And maybe it's more important now than ever for the doctor listeners to take
- 21:25care of themselves, do something fun on their time off work,
- 21:28like you were mentioning, and it just, it can be so frustrating because it just
- 21:32feels like an uphill battle.
- 21:34Yes, I think it is important for people to reach out to colleagues,
- 21:38talk to each other, Look for other sources of reassurance and then,
- 21:43you know, keeping tabs on what's going on as well is important.
- 21:47One pediatric practitioner, she was wondering about incidents,
- 21:53clinic presentation, and infectivity of measles from vaccination.
- 21:57She says, I know it's super rare for them to have a reaction,
- 22:00but she had a nine-month-old patient have a reaction.
- 22:06There can be some reactions from measles vaccines. So overall,
- 22:09it's very well tolerated, right? The measles vaccine has been out since 1963.
- 22:12So we have decades of experience with it, which is great.
- 22:15Some patients have very little side effects or no side effects at all.
- 22:19The most common side effect we see is soreness and redness at the injection
- 22:22site in the arm, right, which is similar to other vaccines.
- 22:26And then some children will develop some stiffness in their joints and they can have some fever.
- 22:31It is also possible, it's much less common, but it's possible a few days after
- 22:35the vaccine to develop a rash, similar to the measles rash, but children that
- 22:40develop that are not contagious to others.
- 22:42It's not true measles, but it looks very much like measles and it can be associated with a fever.
- 22:46Serious side effects from the vaccine are very rare. They should be reported
- 22:50if they occur, but overall the vaccine is very well tolerated.
- 22:53That's great to know and that's reassuring. Have you heard of there's some parents
- 22:58requesting and some parents are getting their baby vaccinated sooner?
- 23:04Yes, it is recommended. So a lot of people are asking about getting extra doses
- 23:08of measles vaccine, and that's not recommended.
- 23:10But what is recommended is if you're planning to travel and you have a child
- 23:14that is less than 12 months of age, so the routine vaccine schedule is you get
- 23:19the first dose at 12 months of age or one year, and then the second dose of
- 23:22age is four to six years of age.
- 23:24But if you have a child that's between six to 12 months, so six to 11 months,
- 23:29and you're going to be traveling internationally, it is recommended that you
- 23:31give a dose of the MMR to that child so that they'll be protected when you're
- 23:36traveling internationally, since we are seeing increased cases of measles globally.
- 23:40Now, they'll still need to get their two doses when they return,
- 23:44you know, one year of age and between four to six years of age.
- 23:47It doesn't count as early credit for that, but it's a way that you can protect
- 23:51a child between six and 11 months of age from that risk of measles if they're
- 23:56traveling internationally.
- 23:57So really, they would get some kids, babies are getting an extra dose,
- 24:02and that's okay, but they still would need to stay on the, in addition to that,
- 24:06stay on the regular schedule.
- 24:08That's right. Yes, that's the nice way to summarize it.
- 24:11Okay, because then I think pediatricians are getting asked a lot about getting an early dose.
- 24:17Yes. Anything else, anything else, Jason, you want to say to pediatric practitioners
- 24:23or family practice doctors in general?
- 24:26Yeah, it's also important for any adults that are unclear, if they're up to
- 24:31speed on their vaccine, to talk with their provider as well.
- 24:33So they're around the children, they could get sick themselves,
- 24:36and so they should make sure that they're also up to speed and they've received
- 24:39the two doses of vaccine.
- 24:42The way that you're analyzing things, do you see this summer places where there's
- 24:48not any sort of, there's not been a reported case,
- 24:51things really amping up this summer or anything you want to say there?
- 24:58It's always tricky to predict, right? But, you know, at this rate,
- 25:03we are still seeing a number of cases.
- 25:05And we're seeing with the widespread nature of these, the concern is always
- 25:09that you're going to see an active case in an area with much lower rates of
- 25:14infection. So a little pocket of infection.
- 25:16This outbreak in Gaines County is largely associated with an area of under-vaccinated
- 25:23community, a Mennonite community that had a much lower vaccine rate.
- 25:27And so if you were to see an active case in another area with a lower vaccine
- 25:33uptake rate, you could see another outbreak.
- 25:34And so each time we see more cases in more states, you always worry you're going
- 25:38to see that intersection of a transmissible person with a susceptible population.
- 25:43So I think we're going to have to keep a close eye on it.
- 25:47And it doesn't sound like the summer travel season is going to help.
- 25:51That's right. The more travel we have, the more mixing we have,
- 25:54and the more chances we have for that intersection of a transmissible person to a susceptible host.
- 26:00Would you be surprised if we don't get a case in Bexar County where we are?
- 26:06I wouldn't be surprised if we had a case, I guess is the way I would say it.
- 26:10I'm hopeful that we don't, but with cases that we've seen in Travis County,
- 26:15Harris County, and then the one in Atascosa, I would not at all be surprised if we have a case.
- 26:22This is so helpful, Dr. Bolling. Before we wrap up for the practitioners,
- 26:27anything else you want to mention about measles that we did not cover?
- 26:30We covered a lot of the important points. I think it's really important to,
- 26:36again, stress the importance of vaccine.
- 26:39We don't have antivirals for treatment after someone gets sick.
- 26:43Children bear the brunt of the real problems of severe illness,
- 26:46hospitalizations, pneumonia, which can lead to death, the most common cause of death with measles.
- 26:52Kids can also have bacterial infections afterwards, too, when children have a case of measles.
- 26:58It suppresses their immune system temporarily, and so they're at higher risk
- 27:02of bacterial infections following that, which is another problem that parents
- 27:06of children should know about.
- 27:08There's multiple risks if you do develop measles.
- 27:10It's not something that just happens and goes away.
- 27:13The more people that we have that have measles, unfortunately,
- 27:15the more chances we have of having another severe case and potentially even another tragic death.
- 27:20Yeah. So we know that measles causes fever, causes itchy, watery eyes,
- 27:25cough, runny nose, and a rash.
- 27:27Other complications, I think, are sometimes not as well known,
- 27:30especially to parents of kids that are considering vaccines.
- 27:34About 1 in 10 people with measles will develop diarrhea. That's probably the
- 27:38most common complication.
- 27:39Children, about 1 in 10 will get otitis media, which is obviously problematic for them.
- 27:45Ear infections, exactly. 1 in 20 will develop pneumonia.
- 27:49And that viral pneumonia can be very serious. 1 in 5 kids gets hospitalized
- 27:53with measles, a lot of them with respiratory complications.
- 27:571 out of 20 can get a viral pneumonia. We don't have a treatment for that.
- 28:01It's the most common cause of death with measles. The death rate for measles
- 28:06is about 1 to 3 out of 1,000.
- 28:08And then about 1 in 1,000 kids can get encephalitis or swelling in the brain. They can have seizures.
- 28:13And they can have long-term complications like deafness or delays in cognitive
- 28:18challenges from inflammation from the encephalitis.
- 28:22So there's some serious consequences that can happen from measles.
- 28:25It's more than just a viral rash that goes away that people used to get in the past.
- 28:29So long-term brain damage can occur. Long-term brain damage can occur.
- 28:33There's even a condition called, the letters are SSPE or subacute sclerosing panencephalitis.
- 28:38It's pretty rare, so we don't have a lot of data on it.
- 28:41Back when we used to have more measles, about 7 to 11 kids out of 100,000 could develop this.
- 28:47This is a neurologic condition that happens about 7 to 10 years after the measles.
- 28:53So the kids have recovered from measles, they're doing better,
- 28:56and then they develop this debilitating, progressive, and universally fatal
- 29:01neurologic condition called SSPE. PE.
- 29:04But so that's something we saw when we had more cases of measles.
- 29:07It doesn't happen very often.
- 29:09It starts to be either delayed immunologic response or a variant of the virus,
- 29:14but it happened so infrequently. We don't have a lot of data on it,
- 29:17but it's obviously extremely concerning, severe consequence that can occur rarely
- 29:22with measles infection. Awful.
- 29:24Kids who get pneumonia from measles, is it otherwise healthy kids or is it mostly
- 29:29kids who have an underlying lung condition?
- 29:32Great question. It can happen in healthy kids that don't have underlying lung conditions.
- 29:37So underlying lung conditions can increase the chances of infections,
- 29:41but a measles viral pneumonia can occur in children with no health problems.
- 29:45They can also develop bacterial supra-infections, again, from that temporary
- 29:50suppression of the immune system, and that can cause, you can get a bacterial pneumonia,
- 29:54bacterial otitis on top of the viral otitis, but you can see a viral pneumonia
- 29:59at a completely healthy child.
- 30:02Dr. Bolling, thank you so much for doing this interview. It's really been insightful.
- 30:07And thank you so much for being here on Pediatrics Now. Thank you so much.