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Do GLP-1s Work for Depression—or Is It Metabolism?

GLP-1 medications like semaglutide have been widely discussed as breakthrough treatments for weight loss and metabolic health. But a large new study published in The Lancet Psychiatry is shifting the conversation toward something deeper: the connection between metabolic health and mental health.

In this video, Dr. Bret Scher breaks down what the research actually shows, and just as importantly, what it doesn’t.

The study analyzed health records from over 95,000 individuals with type 2 diabetes and depression or anxiety. Those taking GLP-1 medications showed a lower risk of severe psychiatric…

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