136. Dr. Goodenowe: Plasmalogens and the Hidden Science of Longevity

Extend Podcast with Darshan Shah, MD · Feb 5, 2026 · 1h 8m

Most people think brain aging is inevitable. What if the real future of longevity is protecting cellular health long before symptoms appear.

In this episode of Extend, we sit down with Dr. Dayan Goodenowe, neuroscientist and biochemist, to explore the hidden role of plasmalogens in brain health, aging, and all-cause mortality. Dr. Goodenowe shares how his work in advanced metabolomics revealed that declining plasmalogen levels can predict dementia, cancer recurrence, and shortened lifespan years before disease is diagnosed, reframing aging as a loss of health rather than a disease itself.

We…