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Psychedelic 5-MeO-DMT induces slow waves in the brain of awake mice
In this edition of Sleep Science Friday, Dr. Lyudmila Korostovtseva (Chair of the ESRS Digital and Communication Committee) speaks with Dr. Benjamin Bréant about his recent study investigating the effects of the psychedelic compound 5-MeO-DMT on brain activity and behaviour in mice.
The study reports the emergence of slow-wave activity typically associated with NREM sleep during behavioural wakefulness, alongside neuronal off-periods and suppression of theta rhythm. The findings indicate a dissociated brain state combining electrophysiological features of sleep with behavioural features of…
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