Perimenopause, Sleep and Hormone Therapy Discussion

The Vagina Doctor Podcast w/ Duncan Turner M.D. · Jun 25, 2026 · 5m

Perimenopause, Sleep Disruption, and Hormone Therapy Options (Estrogen vs Progesterone) | The Vagina Doctor Podcast

Duncan Turner MD and Sophie Mengele NP role-play a gynecologist visit with a 45-year-old patient who suspects perimenopause due to irregular heavier periods, mood changes, hot flashes, and especially disrupted sleep. The clinician explains that perimenopause is challenging because ovarian hormone output becomes unpredictable, with fluctuating estrogen and inconsistent progesterone depending on irregular ovulation, making random blood tests less useful; checking FSH early in the…