1047-Organoid Models Emulating Metastatic Niches
Recent medical reviews highlight the development of human-induced pluripotent stem cell-derived organoids as a transformative tool for studying cancer metastasis. Traditional research relies heavily on rodent models, which often fail to reflect human physiology or support the large-scale screening necessary for drug discovery. By combining these 3D tissue structures with cancer cells, researchers create "chimeroids" that simulate how tumors colonize specific organs like the brain, lungs, liver, and bone. These advanced systems are evolving from simple cell clusters into multilineage niches…
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