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Drug Reverses Fatty Liver by Healing Gut | Science News
A breakthrough drug, DT-109, developed by Michigan Medicine researchers, could revolutionize treatment for severe fatty liver disease by repairing the gut barrier and blocking harmful toxins from reaching the liver. Targeting the gut-liver connection, this glycine-based tripeptide neutralizes damage caused by a harmful gut bacterium, Clostridium perfringens, which produces ammonia that inflames the liver. In primate trials, DT-109 dramatically reduced liver inflammation and improved MASH severity—offering hope for a new therapeutic approach. Beyond liver health, its potential extends to heart…
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