ER-Positive Metastatic Breast Cancer | Oncology Today with Dr Neil Love: Overcoming Endocrine Resistance in ER-Positive Metastatic Breast Cancer

Research To Practice | Oncology Videos · Mar 26, 2024 · 1h 19m

Featuring perspectives from Dr Seth Wander, including the following topics:

Case: A woman in her mid-50s with ER-positive, PR-negative, HER2 IHC 1+ metastatic breast cancer (mBC), Recurrence Score® (RS) = 35 (0:00)

Mechanisms of resistance to antiestrogen therapy in HR-positive mBC (2:33)

Optimal approaches to biomarker assessment (15:37)

Case (continued): A woman in her mid-50s with ER-positive, PR-negative, HER2 IHC 1+ mBC, RS = 35 (18:27)

Case: A woman in her early 60s with de novo HR-positive, HER2-negative mBC with an ESR1 mutation after disease progression on first-line…