Peptides and Hot Flashes: Calming the Thermostat and Taking Back Control
Hot flashes aren’t just an estrogen issue — they’re a brain signaling issue. In this episode, we break down what’s really happening in the hypothalamus during perimenopause, menopause, and surgical menopause, and why vasomotor symptoms can feel sudden, intense, and completely out of control. You’ll learn how specific peptides influence temperature regulation, nervous system balance, and hormonal signaling, including a deep dive into PE-22-28 and the neurokinin B pathway that directly drives hot flashes. We also cover kisspeptin, gonadorelin, Selank, Semax, growth hormone peptides, and…
The skinny
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