Dr. Iyengar, Dr. Bhave & Dr. Mahtani – ESR1 Monitoring & Camizestrant in Metastatic Breast Cancer

Community Health Media · May 8, 2026 · 31m

Can molecular monitoring help clinicians intervene earlier to extend the benefit of first-line therapy?

In this episode of CHM Conversations, Dr. Neil Iyengar, Dr. Manali Bhave, and Dr. Reshma Mahtani discuss overcoming resistance in HR+ mBC.

The conversation focuses on the SERENA-6 trial and the strategy of using serial ctDNA monitoring to catch ESR1 mutations before radiographic progression. Dr. Neil Iyengar, Dr. Manali Bhave, and Dr. Reshma Mahtani break down the practicalities of sequencing endocrine therapies and other targeted therapies, and specifically how a proactive switch to…