Latest / Silver FM 100.6 / Should I take a probiotic? And other gut questions, answered
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- 1:00Speaker 3: Scientists know that our microbiome, it's not just involved in digestion.
- 1:05Speaker 3: It's intimately linked with so much of.
- 1:07Speaker 1: Our overall health.
- 1:10Speaker 3: It influences our immune system, our mental health, our cognition,
- 1:15Speaker 3: and much much more. Some of these links are only
- 1:17Speaker 3: beginning to be fully revealed.
- 1:19Speaker 6: You're listening to Life Kit. I'm Mariyel Sagata and that
- 1:23Speaker 6: was NPR Health correspondent Will Stone. The gut microbiome is
- 1:27Speaker 6: a way of describing the literally trillions of microbes that
- 1:31Speaker 6: populate our intestines.
- 1:32Speaker 3: A lot of these are bacteria, but we also have
- 1:35Speaker 3: other organisms in there, fungi and viruses. So you want
- 1:39Speaker 3: to picture this packed, dense ecosystem that's alive within you.
- 1:44Speaker 6: Now, given what scientists are discovering that the microbiome is
- 1:47Speaker 6: important to our health, people want to hack it. They
- 1:50Speaker 6: want to have the very best, healthiest microbiome possible, Will says.
- 1:56Speaker 6: The problem is the science hasn't come quite that far yet.
- 2:00Speaker 3: Scientists haven't quite figured out how to even define what
- 2:04Speaker 3: is a healthy microbiome. There's a lot of variability when
- 2:08Speaker 3: you look around the world, depending on where you live,
- 2:11Speaker 3: your diet, all kinds of things, and so unless you
- 2:15Speaker 3: are acutely ill and you are having symptoms, it's hard
- 2:18Speaker 3: to pin down what is healthy.
- 2:21Speaker 6: We do have some clues though. It seems that the
- 2:23Speaker 6: more diverse your gut bacteria are, the better. Also, if
- 2:26Speaker 6: your microbiome bounces back well from disruption like antibiotic use,
- 2:31Speaker 6: that's a good sign.
- 2:32Speaker 3: And another area that scientists can look at are the
- 2:35Speaker 3: different groups of bacteria that are present in your microbiome,
- 2:39Speaker 3: and we know that some are associated with better health
- 2:43Speaker 3: when you look around the world. You see this.
- 2:47Speaker 6: On this episode of Life Kit Best Practices for your
- 2:50Speaker 6: Gut Microbiome, I talked to Will about probiotic supplements, microbiome tests,
- 2:55Speaker 6: and what you eat, which is still the most important
- 2:58Speaker 6: factor here.
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- 4:38Speaker 6: this episode. Well, there's a huge market for gut microbiome tests.
- 4:49Speaker 6: Are any of these worth spending money on?
- 4:51Speaker 3: The short answer is generally no, at least when you
- 4:55Speaker 3: look around the huge variety of products out there, and
- 4:58Speaker 3: that's because they tend to overstate the science and be
- 5:02Speaker 3: way ahead of the evidence. So just to run through
- 5:06Speaker 3: a couple of these, you have these gut microbiome tests
- 5:08Speaker 3: that you can buy. They're quite popular, and this isn't
- 5:11Speaker 3: a test that your doctor orders because they think you
- 5:14Speaker 3: have some illness. This is a test you would get
- 5:17Speaker 3: commercially a couple hundred dollars to try to maybe optimize
- 5:20Speaker 3: your microbiome or figure out what's wrong with it on
- 5:23Speaker 3: your own. They'll give you hundreds of different measurements and
- 5:28Speaker 3: it looks pretty legit. I talked to doctor Alexander Koritz
- 5:32Speaker 3: about them. He's a GI specialist and researcher at the
- 5:36Speaker 3: University of Minnesota. He says he'll get patients who are
- 5:39Speaker 3: worried about their gut health, maybe they'll have some symptoms,
- 5:42Speaker 3: and they'll send him their results.
- 5:44Speaker 2: He usually comes as an entire book, colorful with many
- 5:48Speaker 2: many entries of different bacterial species, fungal species, different tabolites.
- 5:55Speaker 2: And I think the message the patient gets, well, jee
- 5:59Speaker 2: might doctor never did this kind of test thing, this,
- 6:03Speaker 2: this amount of information, this is this looks very impressive.
- 6:07Speaker 2: It must mean something, And the reality is it's unfortunately,
- 6:13Speaker 2: it's not very informative at all.
- 6:15Speaker 3: And the fundamental problem is when we already discussed, which
- 6:18Speaker 3: is we don't have a definite consensus on what even
- 6:22Speaker 3: is a healthy microbiome. But beyond that, We've also seen
- 6:26Speaker 3: research that shown the same patient with the same sample
- 6:31Speaker 3: can send it to different companies and they get very
- 6:33Speaker 3: different results. So it's not just interpretation. It's also kind
- 6:37Speaker 3: of the reliability and variability you can get when you
- 6:39Speaker 3: go out onto the market.
- 6:41Speaker 6: Okay, so don't bother with the tests. And what about
- 6:45Speaker 6: supplements like probiotics. For instance, if you walk into a
- 6:49Speaker 6: health food store, there'll be shelves of many different probiotic
- 6:53Speaker 6: capsules you can choose from.
- 6:56Speaker 3: Yeah, and it can be pretty confusing, you know, to
- 6:58Speaker 3: figure out is any of this it's worth my money. Now,
- 7:02Speaker 3: probiotics can be helpful in specific circumstances. So, for example,
- 7:07Speaker 3: there's good evidence they can be beneficial for reducing the
- 7:10Speaker 3: risk of diarrhea associated with antibiotic use, also for preventing
- 7:15Speaker 3: traveler's diarrhea, or for preterm infants who are at risk of complications.
- 7:20Speaker 3: These are a few examples where we have better data.
- 7:22Speaker 3: But beyond that, the idea that most people who are
- 7:26Speaker 3: otherwise healthy should be taking a probiotic daily to support
- 7:30Speaker 3: their gut health, it's really not backed by science yet.
- 7:33Speaker 3: There may be a day where we actually have more
- 7:36Speaker 3: targeted probiotics that can help people, but we are just
- 7:39Speaker 3: not at that point yet.
- 7:41Speaker 6: And for the cases that you mentioned, it's only certain
- 7:45Speaker 6: strains that help with those things, right, Like, you need
- 7:48Speaker 6: to pay attention to which strain you're using if you
- 7:53Speaker 6: want to, for instance, prevent travelers diarrhea.
- 7:56Speaker 9: That's right.
- 7:56Speaker 3: Certain strains have been tested in high quality trials and
- 8:00Speaker 3: been shown to be effective. One point that was made
- 8:03Speaker 3: to me was you'll see sometimes marketing on these probiotics
- 8:07Speaker 3: saying clinically tested. That didn't say they were effective, It
- 8:11Speaker 3: just said they were tested. So you have to be
- 8:14Speaker 3: mindful about what's actually being promised here and then what
- 8:17Speaker 3: can be delivered by the evidence. I spoke to Hannah
- 8:20Speaker 3: Holscher about this. She's at the University of Illinois Orbana Champaign,
- 8:23Speaker 3: and she pointed me to a website called Usprobioticguide dot
- 8:27Speaker 3: com that outlines in a very simple way the levels
- 8:31Speaker 3: of evidence for each strain that's been studied and for
- 8:33Speaker 3: which conditions.
- 8:34Speaker 6: Okay, so what can people do, if anything, to try
- 8:40Speaker 6: to optimize their gut microbiome.
- 8:43Speaker 3: Yeah. The first place to start and how you can
- 8:46Speaker 3: make the most difference by far isn't any special gut
- 8:50Speaker 3: hack or magic solution. It's simple stuff that all of
- 8:54Speaker 3: us already know we should be doing for our overall health.
- 8:57Speaker 3: And that's because our gut microbiome evolved with us, and
- 9:01Speaker 3: when we are healthy and thriving, so to our gut bacteria.
- 9:06Speaker 3: Take a listen to doctor Fergus Shanahan. He's at the
- 9:08Speaker 3: National Institute of Ireland and Cork and a longtime researcher
- 9:12Speaker 3: and gut health.
- 9:12Speaker 10: Like good sleep, plenty of exercise, fresh air, good food,
- 9:17Speaker 10: good food meaning real food and not lots of low
- 9:21Speaker 10: fiber ultra processed foods. Your mother probably told you all
- 9:25Speaker 10: these things in different language, but all the things you
- 9:27Speaker 10: were ever told, they're all good for your microbiome as well.
- 9:30Speaker 10: There isn't any need for some health guru to come
- 9:33Speaker 10: along and say, oh, I've got some major potion now
- 9:35Speaker 10: that's going to improve your microbiome.
- 9:37Speaker 3: Basically, he's like the gut researchers don't have some secret
- 9:42Speaker 3: that they've been keeping from us that we all should know.
- 9:45Speaker 1: It's just not the case yet.
- 9:47Speaker 6: Any specifics that you learned about diet what we should
- 9:50Speaker 6: be eating.
- 9:51Speaker 3: Yeah, number one, without a doubt. Fiber and folks may
- 9:55Speaker 3: have heard this, but most of us do not get
- 9:57Speaker 3: enough fiber just in the general kind of Western die
- 10:00Speaker 3: than most of us have. So you want to aim
- 10:02Speaker 3: for anywhere from about twenty grams a day to forty
- 10:05Speaker 3: depending on your age and sex. Thirty five grams is
- 10:08Speaker 3: generally a good target. And it's not only the quantity
- 10:12Speaker 3: of fiber. You want to make sure you're eating different
- 10:15Speaker 3: types of fiber, because this diversity in your diet ends
- 10:19Speaker 3: up really supporting the microbes in your gut. I spoke
- 10:22Speaker 3: to Hannah Holscher about this, and here's the advice she gave.
- 10:25Speaker 11: If you picture the rainbow of types of foods that
- 10:28Speaker 11: you can eat, fruits, vegetables, whole grains, nuts, and legomes,
- 10:32Speaker 11: you're going to see all of these different colors of
- 10:34Speaker 11: the rainbow. And that means these foods have different phytonutrients
- 10:37Speaker 11: in them, and they have different fibers, and just like
- 10:40Speaker 11: an apple tastes very different from an orange and tastes
- 10:44Speaker 11: different from an avocado or broccoli, you know, they have
- 10:47Speaker 11: different fibers in them and different phytonutrients, and different microbes
- 10:51Speaker 11: can go in and use those fibers as energy sources.
- 10:56Speaker 3: Hannah has spent a lot of time doing well controlled
- 11:00Speaker 3: where they feed people different foods and then see how
- 11:03Speaker 3: that can influence your gut microbiome. One example, they did
- 11:07Speaker 3: a trial with walnuts and they found that it enriched
- 11:10Speaker 3: a bacteria called rose Buria, which is beneficial and linked
- 11:14Speaker 3: to positive health. We do have some data showing that
- 11:17Speaker 3: fermented food in particular can be pretty beneficial for lowering
- 11:22Speaker 3: inflammation and overall got microbiome diversity in health. So these
- 11:28Speaker 3: are things like sauer kraut, kim chi, yogurt, but you
- 11:32Speaker 3: want to look and see whether the yogurt has live
- 11:35Speaker 3: cultures of bacteria in it, not highly processed kinds of
- 11:39Speaker 3: yogurt with sugar and they don't actually have bacteria in it.
- 11:42Speaker 3: Those are a couple examples of beneficial probiotics that you
- 11:46Speaker 3: can get from your food.
- 11:48Speaker 6: Okay, and then is there anything that people should avoid
- 11:52Speaker 6: to help their gut microbiome?
- 11:54Speaker 3: Yeah, so probably no big surprise here unless you really
- 11:58Speaker 3: need it. Antibiotics tend to be overused, overprescribed, so try
- 12:03Speaker 3: to avoid those when not necessary. Beyond that, Hannah and
- 12:07Speaker 3: others brought up some of the usual culprits we hear
- 12:10Speaker 3: when we talk about other issues with our health foods
- 12:13Speaker 3: like highly refined sugary that are low in fiber, sometimes
- 12:18Speaker 3: called ultra processed foods. You want to try to keep
- 12:21Speaker 3: those to a minimum. And you know, she's an advocate
- 12:24Speaker 3: of moderation. You know, doesn't really think people need to
- 12:27Speaker 3: be extreme here, but she says as much as you can. Unfortunately,
- 12:31Speaker 3: alcohol is not great for our gut, and you know
- 12:34Speaker 3: best to avoid that if you're concerned about supporting your
- 12:37Speaker 3: gut microbiome.
- 12:39Speaker 1: Will Stone, thank you so much, thanks for having me.
- 12:41Speaker 1: It was fun all right.
- 12:47Speaker 6: Time for a recap. Don't bother spending money on a
- 12:50Speaker 6: gut microbiome test. They overstate the science and they're way
- 12:53Speaker 6: ahead of the evidence. Some probiotic supplements have been shown
- 12:57Speaker 6: to help with particular problems like travelers diarrhea and diarrhea
- 13:01Speaker 6: associated with antibiotic use, but the idea that most people
- 13:04Speaker 6: who are otherwise healthy should be taking a probiotic daily
- 13:07Speaker 6: to support their gut health is not backed by science yet.
- 13:11Speaker 6: We'll drop the names of a couple strains that are
- 13:13Speaker 6: well studied in the show notes, and you can also
- 13:16Speaker 6: check out a website called Usprobiotic guide dot com, which
- 13:20Speaker 6: outlines the levels of evidence for each strain that's been
- 13:23Speaker 6: studied and for which conditions. Now, the researchers who study
- 13:27Speaker 6: the guts say the best thing you can do for
- 13:29Speaker 6: your gut microbiome is eat enough fiber a day that's
- 13:33Speaker 6: about twenty to forty grams a day, depending on your
- 13:35Speaker 6: age and sex. Eat fermented foods like kimchi and yogurt.
- 13:39Speaker 6: Cut down on ultraprocessed foods and alcohol, and only take
- 13:43Speaker 6: antibiotics when you really need them. Also get enough sleep
- 13:46Speaker 6: and exercise. All right, that's our show.
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- 14:12Speaker 6: This episode of Life Kit was produced by Margaret Serino.
- 14:14Speaker 6: It was edited by Megan Kin, Carmel Roth, and Lauren Gonzalez.
- 14:18Speaker 6: Our digital editor is Malica Garib and our visuals editor
- 14:21Speaker 6: is c J. Rikolon. Our production team also includes Andy Tago,
- 14:25Speaker 6: Claire Marie Schneider, and Sylvie Douglas. Engineering support comes from
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- 14:32Speaker 6: El Sagara. Thanks for listening.
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