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TRF2 Protein Key to Muscle Repair | Science News

Scientists have uncovered a protein called TRF2 that’s far more than just a chromosome protector—it’s the unsung hero of muscle repair. This protein keeps muscle stem cells primed and ready to rebuild tissue after injury. Without TRF2, those cells lose their identity, turning damaged areas into fat and scar instead of muscle. In mice with Duchenne muscular dystrophy, losing TRF2 accelerated disease and shortened lifespan—highlighting its vital role in muscle health. The discovery not only deepens our understanding of regeneration but also hints at why muscle rarely turns cancerous—and could…

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