1662-Tri-Modal Antiplatelet Nanomotors for Arterial Thrombus

Paper Talk · Oct 10, 2026 · 24m

This research article describes the development of a carrier-free antiplatelet nanomotor designed for the advanced treatment of acute arterial thrombosis. The authors engineered a specialized nanosystem by co-assembling a photothermal agent (DiR), a nitric oxide donor (BNN6), and the antiplatelet drug ticagrelor (TGL). When activated by a near-infrared laser, the nanomotor generates vigorous mechanical motion and heat to physically penetrate and disrupt blood clots. Simultaneously, the localized release of nitric oxide and ticagrelor provides a synergistic medicinal effect that inhibits…